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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP5 All Species: 28.18
Human Site: Y355 Identified Species: 44.29
UniProt: Q13451 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13451 NP_001139247.1 457 51212 Y355 S A N E K G L Y R R G E A Q L
Chimpanzee Pan troglodytes XP_001172411 457 51122 Y355 S A N E K G L Y R R G E A Q L
Rhesus Macaque Macaca mulatta XP_001098079 459 51670 F357 S N N E K G L F R R G E A H L
Dog Lupus familis XP_538880 456 51014 Y355 S A N E K G L Y R R G E A Q L
Cat Felis silvestris
Mouse Mus musculus Q64378 456 50948 Y355 S A N E K G L Y R R G E A Q L
Rat Rattus norvegicus Q9QVC8 458 51432 F357 S N N E K G L F R R G E A H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512517 419 46551 Y322 G A N E K G L Y R R G K A R L
Chicken Gallus gallus NP_001005431 449 50409 Y355 Q D N E K G L Y R R G E A R L
Frog Xenopus laevis NP_001084593 447 50080 F353 P S N E K G L F R R G E A F M
Zebra Danio Brachydanio rerio NP_998314 453 51464 Y355 P E N E K A L Y R R G E A R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL78 439 48777 Y335 K N N V K A L Y R R G Q C N L
Honey Bee Apis mellifera XP_395748 459 51510 F337 P Q N E K A L F R R G Q A Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781282 422 47590 F342 A A I K A E E F L E A V S H C
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141458 458 51432 F357 S N N E K G L F R R G E A H L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38931 551 61434 E406 A A S K K K E E G N S K F K G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 54 95.1 N.A. 87 53.7 N.A. 69.8 83.1 55.5 58.6 N.A. 39.3 47 N.A. 44.2
Protein Similarity: 100 99.7 73.8 96.7 N.A. 91.6 72.4 N.A. 77.6 88.8 70.9 75.2 N.A. 56.6 61.2 N.A. 62.8
P-Site Identity: 100 100 80 100 N.A. 100 80 N.A. 80 80 66.6 73.3 N.A. 53.3 60 N.A. 6.6
P-Site Similarity: 100 100 86.6 100 N.A. 100 86.6 N.A. 93.3 86.6 86.6 80 N.A. 60 73.3 N.A. 33.3
Percent
Protein Identity: N.A. 53.7 N.A. 30.1 N.A. N.A.
Protein Similarity: N.A. 72.4 N.A. 47 N.A. N.A.
P-Site Identity: N.A. 80 N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. 86.6 N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 47 0 0 7 20 0 0 0 0 7 0 80 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % C
% Asp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 0 80 0 7 14 7 0 7 0 67 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 40 0 0 0 0 7 7 0 % F
% Gly: 7 0 0 0 0 67 0 0 7 0 87 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 27 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 0 14 94 7 0 0 0 0 0 14 0 7 0 % K
% Leu: 0 0 0 0 0 0 87 0 7 0 0 0 0 0 80 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 27 87 0 0 0 0 0 0 7 0 0 0 7 0 % N
% Pro: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 7 0 0 0 0 0 0 0 0 0 14 0 27 0 % Q
% Arg: 0 0 0 0 0 0 0 0 87 87 0 0 0 20 0 % R
% Ser: 47 7 7 0 0 0 0 0 0 0 7 0 7 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 54 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _