Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUSC3 All Species: 16.36
Human Site: T22 Identified Species: 27.69
UniProt: Q13454 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13454 NP_006756.2 348 39676 T22 R R L R Y L P T G S F P F L L
Chimpanzee Pan troglodytes XP_001140106 359 41005 T22 R R L R Y L P T G S F P F L L
Rhesus Macaque Macaca mulatta XP_001094069 345 39325 T22 R R L R Y L P T G S F P F L L
Dog Lupus familis XP_849445 348 39645 T22 R R L R Y L P T G S F P F L L
Cat Felis silvestris
Mouse Mus musculus Q9CQY5 335 37951 S26 L L V S K V P S A S A Q R K K
Rat Rattus norvegicus O35777 335 37974 R31 V P S A S A Q R K K E K V L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512782 468 52457 S22 G E G R P T G S D C E P H N L
Chicken Gallus gallus Q5ZJ06 328 36743 G22 C G G P R A A G Q K R K E M V
Frog Xenopus laevis Q63ZR0 329 36900 E22 A M C G G L S E G Q K K K E M
Zebra Danio Brachydanio rerio Q7ZV50 328 37403 G22 L H D M R L N G Q K K K E T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609204 330 36992 A24 L F A I Y A A A Q S K S K T G
Honey Bee Apis mellifera XP_395605 330 37476 K26 V C C Q Y R M K N T Q G S S L
Nematode Worm Caenorhab. elegans P34669 331 37670 V22 E D K V Q N L V D L T S R Q S
Sea Urchin Strong. purpuratus XP_782723 331 37476 Q22 L A V I I C D Q Q S Y A V K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 98.5 99.7 N.A. 64.9 65.2 N.A. 58.9 68.3 66.6 66.3 N.A. 54 53.7 45.1 60.6
Protein Similarity: 100 96.6 98.5 99.7 N.A. 81.9 81.3 N.A. 62.8 82.7 82.7 81.6 N.A. 72.1 72.4 66 78.7
P-Site Identity: 100 100 100 100 N.A. 13.3 6.6 N.A. 20 0 13.3 13.3 N.A. 13.3 13.3 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 33.3 13.3 N.A. 26.6 13.3 20 13.3 N.A. 13.3 26.6 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 8 0 22 15 8 8 0 8 8 0 0 0 % A
% Cys: 8 8 15 0 0 8 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 0 8 0 15 0 0 0 0 0 0 % D
% Glu: 8 8 0 0 0 0 0 8 0 0 15 0 15 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 29 0 29 0 0 % F
% Gly: 8 8 15 8 8 0 8 15 36 0 0 8 0 0 8 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 15 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 8 0 0 8 8 22 22 29 15 15 15 % K
% Leu: 29 8 29 0 0 43 8 0 0 8 0 0 0 36 50 % L
% Met: 0 8 0 8 0 0 8 0 0 0 0 0 0 8 8 % M
% Asn: 0 0 0 0 0 8 8 0 8 0 0 0 0 8 0 % N
% Pro: 0 8 0 8 8 0 36 0 0 0 0 36 0 0 0 % P
% Gln: 0 0 0 8 8 0 8 8 29 8 8 8 0 8 0 % Q
% Arg: 29 29 0 36 15 8 0 8 0 0 8 0 15 0 0 % R
% Ser: 0 0 8 8 8 0 8 15 0 50 0 15 8 8 8 % S
% Thr: 0 0 0 0 0 8 0 29 0 8 8 0 0 15 0 % T
% Val: 15 0 15 8 0 8 0 8 0 0 0 0 15 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 43 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _