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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUSC3
All Species:
15.76
Human Site:
Y19
Identified Species:
26.67
UniProt:
Q13454
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13454
NP_006756.2
348
39676
Y19
Q
A
G
R
R
L
R
Y
L
P
T
G
S
F
P
Chimpanzee
Pan troglodytes
XP_001140106
359
41005
Y19
Q
A
G
R
R
L
R
Y
L
P
T
G
S
F
P
Rhesus Macaque
Macaca mulatta
XP_001094069
345
39325
Y19
Q
A
G
R
R
L
R
Y
L
P
T
G
S
F
P
Dog
Lupus familis
XP_849445
348
39645
Y19
Q
A
G
R
R
L
R
Y
L
P
T
G
S
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQY5
335
37951
K23
V
A
L
L
L
V
S
K
V
P
S
A
S
A
Q
Rat
Rattus norvegicus
O35777
335
37974
S28
V
S
K
V
P
S
A
S
A
Q
R
K
K
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512782
468
52457
P19
E
R
L
G
E
G
R
P
T
G
S
D
C
E
P
Chicken
Gallus gallus
Q5ZJ06
328
36743
R19
L
L
A
C
G
G
P
R
A
A
G
Q
K
R
K
Frog
Xenopus laevis
Q63ZR0
329
36900
G19
I
L
F
A
M
C
G
G
L
S
E
G
Q
K
K
Zebra Danio
Brachydanio rerio
Q7ZV50
328
37403
R19
V
V
C
L
H
D
M
R
L
N
G
Q
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609204
330
36992
Y21
V
V
A
L
F
A
I
Y
A
A
A
Q
S
K
S
Honey Bee
Apis mellifera
XP_395605
330
37476
Y23
L
S
Y
V
C
C
Q
Y
R
M
K
N
T
Q
G
Nematode Worm
Caenorhab. elegans
P34669
331
37670
Q19
Q
T
L
E
D
K
V
Q
N
L
V
D
L
T
S
Sea Urchin
Strong. purpuratus
XP_782723
331
37476
I19
V
A
I
L
A
V
I
I
C
D
Q
Q
S
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
98.5
99.7
N.A.
64.9
65.2
N.A.
58.9
68.3
66.6
66.3
N.A.
54
53.7
45.1
60.6
Protein Similarity:
100
96.6
98.5
99.7
N.A.
81.9
81.3
N.A.
62.8
82.7
82.7
81.6
N.A.
72.1
72.4
66
78.7
P-Site Identity:
100
100
100
100
N.A.
20
0
N.A.
13.3
0
13.3
6.6
N.A.
13.3
6.6
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
40
6.6
N.A.
26.6
0
13.3
6.6
N.A.
13.3
26.6
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
15
8
8
8
8
0
22
15
8
8
0
8
8
% A
% Cys:
0
0
8
8
8
15
0
0
8
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
0
8
0
15
0
0
0
% D
% Glu:
8
0
0
8
8
0
0
0
0
0
8
0
0
15
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
29
0
% F
% Gly:
0
0
29
8
8
15
8
8
0
8
15
36
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
15
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
8
0
8
0
0
8
8
22
22
29
% K
% Leu:
15
15
22
29
8
29
0
0
43
8
0
0
8
0
0
% L
% Met:
0
0
0
0
8
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
8
8
0
36
0
0
0
0
36
% P
% Gln:
36
0
0
0
0
0
8
8
0
8
8
29
8
8
8
% Q
% Arg:
0
8
0
29
29
0
36
15
8
0
8
0
0
8
0
% R
% Ser:
0
15
0
0
0
8
8
8
0
8
15
0
50
0
15
% S
% Thr:
0
8
0
0
0
0
0
0
8
0
29
0
8
8
0
% T
% Val:
36
15
0
15
0
15
8
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
43
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _