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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROCK1
All Species:
18.48
Human Site:
S1100
Identified Species:
36.97
UniProt:
Q13464
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13464
NP_005397.1
1354
158175
S1100
K
L
L
D
L
S
D
S
T
S
V
A
S
F
P
Chimpanzee
Pan troglodytes
P61584
1003
117506
Y791
R
Y
G
W
K
K
Q
Y
V
V
V
S
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001091134
1354
158171
S1100
K
L
L
D
L
S
D
S
T
S
V
A
S
F
P
Dog
Lupus familis
XP_537305
2025
232462
S1769
K
L
L
D
L
S
D
S
T
S
I
A
S
F
P
Cat
Felis silvestris
Mouse
Mus musculus
P70335
1354
158152
S1100
K
L
L
D
L
S
D
S
T
S
V
A
S
F
P
Rat
Rattus norvegicus
Q63644
1369
159608
N1115
S
A
D
E
T
D
G
N
L
P
V
G
S
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505615
1400
161955
S1006
T
I
H
I
G
L
D
S
S
S
I
G
S
G
P
Chicken
Gallus gallus
XP_419151
1358
158654
D1104
L
D
L
Q
Q
G
M
D
S
T
S
V
S
S
L
Frog
Xenopus laevis
NP_001154860
1372
159002
D1117
Q
S
L
N
L
G
L
D
S
T
S
I
G
S
G
Zebra Danio
Brachydanio rerio
NP_777288
1375
159755
D1122
S
L
N
V
Q
S
L
D
S
A
S
M
S
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1B0
1637
186706
C1290
K
V
V
E
S
K
N
C
I
S
A
C
T
G
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198244
1323
154677
S1077
M
H
A
S
D
S
A
S
I
N
S
A
G
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
99.6
65.3
N.A.
96.5
94.8
N.A.
58.2
87.3
64.4
62.4
N.A.
24.3
N.A.
N.A.
47.5
Protein Similarity:
100
74
99.8
66.4
N.A.
98.7
97.4
N.A.
72.5
94.2
80.3
79.4
N.A.
45.8
N.A.
N.A.
66.2
P-Site Identity:
100
13.3
100
93.3
N.A.
100
13.3
N.A.
33.3
13.3
13.3
20
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
26.6
100
100
N.A.
100
26.6
N.A.
53.3
26.6
40
33.3
N.A.
46.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
9
0
0
9
9
42
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% C
% Asp:
0
9
9
34
9
9
42
25
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
17
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% F
% Gly:
0
0
9
0
9
17
9
0
0
0
0
17
17
17
17
% G
% His:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
17
0
17
9
0
0
9
% I
% Lys:
42
0
0
0
9
17
0
0
0
0
0
0
0
9
9
% K
% Leu:
9
42
50
0
42
9
17
0
9
0
0
0
0
0
9
% L
% Met:
9
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
9
9
0
0
9
9
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
42
% P
% Gln:
9
0
0
9
17
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
9
0
9
9
50
0
50
34
50
34
9
75
25
0
% S
% Thr:
9
0
0
0
9
0
0
0
34
17
0
0
9
0
0
% T
% Val:
0
9
9
9
0
0
0
0
9
9
42
9
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _