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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ROCK1 All Species: 22.12
Human Site: S1105 Identified Species: 44.24
UniProt: Q13464 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13464 NP_005397.1 1354 158175 S1105 S D S T S V A S F P S A D E T
Chimpanzee Pan troglodytes P61584 1003 117506 S796 K Q Y V V V S S K K I L F Y N
Rhesus Macaque Macaca mulatta XP_001091134 1354 158171 S1105 S D S T S V A S F P S A D E T
Dog Lupus familis XP_537305 2025 232462 S1774 S D S T S I A S F P S A D E T
Cat Felis silvestris
Mouse Mus musculus P70335 1354 158152 S1105 S D S T S V A S F P S A D E T
Rat Rattus norvegicus Q63644 1369 159608 S1120 D G N L P V G S A C I P Y L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505615 1400 161955 S1011 L D S S S I G S G P G E A E A
Chicken Gallus gallus XP_419151 1358 158654 S1109 G M D S T S V S S L Q P D E I
Frog Xenopus laevis NP_001154860 1372 159002 G1122 G L D S T S I G S G H G D T D
Zebra Danio Brachydanio rerio NP_777288 1375 159755 S1127 S L D S A S M S S G P D M D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1B0 1637 186706 T1295 K N C I S A C T G I I R R F P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198244 1323 154677 G1082 S A S I N S A G E A E N G Q G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74 99.6 65.3 N.A. 96.5 94.8 N.A. 58.2 87.3 64.4 62.4 N.A. 24.3 N.A. N.A. 47.5
Protein Similarity: 100 74 99.8 66.4 N.A. 98.7 97.4 N.A. 72.5 94.2 80.3 79.4 N.A. 45.8 N.A. N.A. 66.2
P-Site Identity: 100 13.3 100 93.3 N.A. 100 13.3 N.A. 40 20 6.6 20 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 20 100 100 N.A. 100 20 N.A. 53.3 33.3 20 40 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 42 0 9 9 0 34 9 0 9 % A
% Cys: 0 0 9 0 0 0 9 0 0 9 0 0 0 0 0 % C
% Asp: 9 42 25 0 0 0 0 0 0 0 0 9 50 9 9 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 9 9 0 50 0 % E
% Phe: 0 0 0 0 0 0 0 0 34 0 0 0 9 9 9 % F
% Gly: 17 9 0 0 0 0 17 17 17 17 9 9 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 17 0 17 9 0 0 9 25 0 0 0 9 % I
% Lys: 17 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % K
% Leu: 9 17 0 9 0 0 0 0 0 9 0 9 0 9 0 % L
% Met: 0 9 0 0 0 0 9 0 0 0 0 0 9 0 0 % M
% Asn: 0 9 9 0 9 0 0 0 0 0 0 9 0 0 9 % N
% Pro: 0 0 0 0 9 0 0 0 0 42 9 17 0 0 9 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 9 0 0 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % R
% Ser: 50 0 50 34 50 34 9 75 25 0 34 0 0 0 0 % S
% Thr: 0 0 0 34 17 0 0 9 0 0 0 0 0 9 42 % T
% Val: 0 0 0 9 9 42 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _