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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROCK1
All Species:
13.64
Human Site:
S1108
Identified Species:
27.27
UniProt:
Q13464
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13464
NP_005397.1
1354
158175
S1108
T
S
V
A
S
F
P
S
A
D
E
T
D
G
N
Chimpanzee
Pan troglodytes
P61584
1003
117506
I799
V
V
V
S
S
K
K
I
L
F
Y
N
D
E
Q
Rhesus Macaque
Macaca mulatta
XP_001091134
1354
158171
S1108
T
S
V
A
S
F
P
S
A
D
E
T
D
G
N
Dog
Lupus familis
XP_537305
2025
232462
S1777
T
S
I
A
S
F
P
S
A
D
E
T
D
G
N
Cat
Felis silvestris
Mouse
Mus musculus
P70335
1354
158152
S1108
T
S
V
A
S
F
P
S
A
D
E
T
D
G
N
Rat
Rattus norvegicus
Q63644
1369
159608
I1123
L
P
V
G
S
A
C
I
P
Y
L
F
I
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505615
1400
161955
G1014
S
S
I
G
S
G
P
G
E
A
E
A
D
D
G
Chicken
Gallus gallus
XP_419151
1358
158654
Q1112
S
T
S
V
S
S
L
Q
P
D
E
I
D
G
N
Frog
Xenopus laevis
NP_001154860
1372
159002
H1125
S
T
S
I
G
S
G
H
G
D
T
D
A
E
D
Zebra Danio
Brachydanio rerio
NP_777288
1375
159755
P1130
S
A
S
M
S
S
G
P
D
M
D
T
D
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1B0
1637
186706
I1298
I
S
A
C
T
G
I
I
R
R
F
P
N
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198244
1323
154677
E1085
I
N
S
A
G
E
A
E
N
G
Q
G
M
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
99.6
65.3
N.A.
96.5
94.8
N.A.
58.2
87.3
64.4
62.4
N.A.
24.3
N.A.
N.A.
47.5
Protein Similarity:
100
74
99.8
66.4
N.A.
98.7
97.4
N.A.
72.5
94.2
80.3
79.4
N.A.
45.8
N.A.
N.A.
66.2
P-Site Identity:
100
20
100
93.3
N.A.
100
13.3
N.A.
33.3
40
6.6
20
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
13.3
N.A.
46.6
53.3
26.6
46.6
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
42
0
9
9
0
34
9
0
9
9
0
0
% A
% Cys:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
50
9
9
67
9
9
% D
% Glu:
0
0
0
0
0
9
0
9
9
0
50
0
0
25
0
% E
% Phe:
0
0
0
0
0
34
0
0
0
9
9
9
0
17
0
% F
% Gly:
0
0
0
17
17
17
17
9
9
9
0
9
0
42
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
17
0
17
9
0
0
9
25
0
0
0
9
9
9
0
% I
% Lys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
9
0
0
9
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
9
0
0
9
9
0
50
% N
% Pro:
0
9
0
0
0
0
42
9
17
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% R
% Ser:
34
50
34
9
75
25
0
34
0
0
0
0
0
0
9
% S
% Thr:
34
17
0
0
9
0
0
0
0
0
9
42
0
0
0
% T
% Val:
9
9
42
9
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _