KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROCK1
All Species:
39.39
Human Site:
Y1200
Identified Species:
78.79
UniProt:
Q13464
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13464
NP_005397.1
1354
158175
Y1200
P
K
I
F
Q
I
L
Y
A
N
E
G
E
C
R
Chimpanzee
Pan troglodytes
P61584
1003
117506
C891
L
Y
H
F
P
A
N
C
D
A
C
A
K
P
L
Rhesus Macaque
Macaca mulatta
XP_001091134
1354
158171
Y1200
P
K
I
F
Q
I
L
Y
A
N
E
G
E
C
R
Dog
Lupus familis
XP_537305
2025
232462
Y1869
P
K
I
F
Q
I
L
Y
A
N
E
G
E
C
R
Cat
Felis silvestris
Mouse
Mus musculus
P70335
1354
158152
Y1200
P
K
I
F
Q
I
L
Y
A
N
E
G
E
C
R
Rat
Rattus norvegicus
Q63644
1369
159608
Y1215
P
K
I
F
Q
I
L
Y
A
N
E
G
E
C
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505615
1400
161955
Y1106
P
R
I
F
Q
I
L
Y
A
N
E
G
E
S
K
Chicken
Gallus gallus
XP_419151
1358
158654
Y1204
P
K
I
F
Q
I
L
Y
A
N
E
G
E
C
R
Frog
Xenopus laevis
NP_001154860
1372
159002
Y1217
P
R
I
F
Q
I
L
Y
A
N
E
G
E
S
K
Zebra Danio
Brachydanio rerio
NP_777288
1375
159755
Y1222
P
R
I
F
Q
I
L
Y
A
N
E
G
E
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1B0
1637
186706
N1390
N
Q
L
C
A
F
L
N
Y
S
G
V
D
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198244
1323
154677
Y1177
P
R
I
F
Q
L
L
Y
A
G
E
G
E
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
99.6
65.3
N.A.
96.5
94.8
N.A.
58.2
87.3
64.4
62.4
N.A.
24.3
N.A.
N.A.
47.5
Protein Similarity:
100
74
99.8
66.4
N.A.
98.7
97.4
N.A.
72.5
94.2
80.3
79.4
N.A.
45.8
N.A.
N.A.
66.2
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
80
100
80
80
N.A.
6.6
N.A.
N.A.
73.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
100
93.3
93.3
N.A.
33.3
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
0
0
84
9
0
9
0
9
0
% A
% Cys:
0
0
0
9
0
0
0
9
0
0
9
0
0
50
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
84
0
84
0
0
% E
% Phe:
0
0
0
92
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
9
84
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
84
0
0
75
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
50
0
0
0
0
0
0
0
0
0
0
9
0
25
% K
% Leu:
9
0
9
0
0
9
92
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
9
9
0
75
0
0
0
9
0
% N
% Pro:
84
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
9
0
0
84
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
59
% R
% Ser:
0
0
0
0
0
0
0
0
0
9
0
0
0
25
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
84
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _