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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROCK1
All Species:
25.45
Human Site:
Y913
Identified Species:
50.91
UniProt:
Q13464
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13464
NP_005397.1
1354
158175
Y913
R
G
L
L
E
E
Q
Y
F
E
L
T
Q
E
S
Chimpanzee
Pan troglodytes
P61584
1003
117506
A656
T
Q
A
V
N
K
L
A
E
I
M
N
R
K
D
Rhesus Macaque
Macaca mulatta
XP_001091134
1354
158171
Y913
R
G
L
L
E
E
Q
Y
F
E
L
T
Q
E
S
Dog
Lupus familis
XP_537305
2025
232462
Y1582
R
G
L
L
E
E
Q
Y
F
E
L
T
Q
E
S
Cat
Felis silvestris
Mouse
Mus musculus
P70335
1354
158152
Y913
R
G
I
L
E
E
Q
Y
F
E
L
T
Q
E
S
Rat
Rattus norvegicus
Q63644
1369
159608
Y913
R
G
I
L
E
E
Q
Y
F
E
L
T
Q
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505615
1400
161955
E847
A
T
I
G
S
L
E
E
A
N
R
T
L
T
S
Chicken
Gallus gallus
XP_419151
1358
158654
Y915
R
A
L
L
E
E
Q
Y
F
E
L
S
Q
E
S
Frog
Xenopus laevis
NP_001154860
1372
159002
K929
Y
S
D
L
E
K
E
K
I
M
K
E
L
E
I
Zebra Danio
Brachydanio rerio
NP_777288
1375
159755
K929
Y
S
D
L
E
K
E
K
I
M
K
E
L
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1B0
1637
186706
F1140
K
K
D
V
P
C
I
F
K
I
K
T
A
L
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198244
1323
154677
Y871
R
T
I
A
E
D
Q
Y
T
D
L
E
R
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
99.6
65.3
N.A.
96.5
94.8
N.A.
58.2
87.3
64.4
62.4
N.A.
24.3
N.A.
N.A.
47.5
Protein Similarity:
100
74
99.8
66.4
N.A.
98.7
97.4
N.A.
72.5
94.2
80.3
79.4
N.A.
45.8
N.A.
N.A.
66.2
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
13.3
86.6
20
20
N.A.
6.6
N.A.
N.A.
40
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
26.6
93.3
33.3
33.3
N.A.
26.6
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
9
0
0
0
9
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
0
0
9
0
0
0
9
0
0
0
0
9
% D
% Glu:
0
0
0
0
75
50
25
9
9
50
0
25
0
75
0
% E
% Phe:
0
0
0
0
0
0
0
9
50
0
0
0
0
0
0
% F
% Gly:
0
42
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
34
0
0
0
9
0
17
17
0
0
0
0
25
% I
% Lys:
9
9
0
0
0
25
0
17
9
0
25
0
0
9
9
% K
% Leu:
0
0
34
67
0
9
9
0
0
0
59
0
25
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
17
9
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
9
0
9
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
59
0
0
0
0
0
50
0
0
% Q
% Arg:
59
0
0
0
0
0
0
0
0
0
9
0
17
0
0
% R
% Ser:
0
17
0
0
9
0
0
0
0
0
0
9
0
0
59
% S
% Thr:
9
17
0
0
0
0
0
0
9
0
0
59
0
9
0
% T
% Val:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _