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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZD5 All Species: 20.91
Human Site: S11 Identified Species: 41.82
UniProt: Q13467 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13467 NP_003459.2 585 64507 S11 P D P S A P P S L L L L L L A
Chimpanzee Pan troglodytes XP_526008 585 64475 S11 P D P S A P P S L L L L L L A
Rhesus Macaque Macaca mulatta XP_001096837 635 68033 A14 L E V T S L L A A L A L L Q R
Dog Lupus familis XP_545614 589 64543 S11 P D P C A P P S L L L L L L A
Cat Felis silvestris
Mouse Mus musculus Q9EQD0 585 64119 S11 P D P S A P P S L L L L L L A
Rat Rattus norvegicus Q8CHL0 585 64093 S11 P D P S A P P S L L L L L L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9IA06 523 59263
Frog Xenopus laevis P58421 559 63500 V8 M G S F R S G V F A L S F V V
Zebra Danio Brachydanio rerio NP_571209 592 66471 T11 P A D E H H F T M E T S G M H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVX3 694 75433 A22 L L L T S C R A D G P L H S A
Honey Bee Apis mellifera XP_397259 711 74000 S49 S S S S S S S S M V G G V P G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188449 555 62346
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 60.9 96.2 N.A. 96.2 96.4 N.A. N.A. 45.2 73.3 71.1 N.A. 50.8 48.9 N.A. 61.3
Protein Similarity: 100 99.6 69.1 96.7 N.A. 97.2 97.6 N.A. N.A. 58.9 81.1 78.5 N.A. 60.9 60.2 N.A. 72.3
P-Site Identity: 100 100 20 93.3 N.A. 100 100 N.A. N.A. 0 6.6 6.6 N.A. 13.3 13.3 N.A. 0
P-Site Similarity: 100 100 46.6 93.3 N.A. 100 100 N.A. N.A. 0 13.3 26.6 N.A. 33.3 40 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 42 0 0 17 9 9 9 0 0 0 50 % A
% Cys: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 42 9 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 9 0 9 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 9 0 9 0 0 0 9 0 0 % F
% Gly: 0 9 0 0 0 0 9 0 0 9 9 9 9 0 9 % G
% His: 0 0 0 0 9 9 0 0 0 0 0 0 9 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 9 9 0 0 9 9 0 42 50 50 59 50 42 0 % L
% Met: 9 0 0 0 0 0 0 0 17 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 0 42 0 0 42 42 0 0 0 9 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 9 % R
% Ser: 9 9 17 42 25 17 9 50 0 0 0 17 0 9 0 % S
% Thr: 0 0 0 17 0 0 0 9 0 0 9 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 9 0 9 0 0 9 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _