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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZD5 All Species: 17.88
Human Site: S7 Identified Species: 35.76
UniProt: Q13467 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13467 NP_003459.2 585 64507 S7 _ M A R P D P S A P P S L L L
Chimpanzee Pan troglodytes XP_526008 585 64475 S7 _ M A R P D P S A P P S L L L
Rhesus Macaque Macaca mulatta XP_001096837 635 68033 T10 W G Y L L E V T S L L A A L A
Dog Lupus familis XP_545614 589 64543 C7 _ M A R P D P C A P P S L L L
Cat Felis silvestris
Mouse Mus musculus Q9EQD0 585 64119 S7 _ M A R P D P S A P P S L L L
Rat Rattus norvegicus Q8CHL0 585 64093 S7 _ M A R P D P S A P P S L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9IA06 523 59263
Frog Xenopus laevis P58421 559 63500
Zebra Danio Brachydanio rerio NP_571209 592 66471 E7 _ M R K P A D E H H F T M E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVX3 694 75433 T18 L G L V L L L T S C R A D G P
Honey Bee Apis mellifera XP_397259 711 74000 S45 S S S S S S S S S S S S M V G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188449 555 62346
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 60.9 96.2 N.A. 96.2 96.4 N.A. N.A. 45.2 73.3 71.1 N.A. 50.8 48.9 N.A. 61.3
Protein Similarity: 100 99.6 69.1 96.7 N.A. 97.2 97.6 N.A. N.A. 58.9 81.1 78.5 N.A. 60.9 60.2 N.A. 72.3
P-Site Identity: 100 100 6.6 92.8 N.A. 100 100 N.A. N.A. 0 0 14.2 N.A. 0 13.3 N.A. 0
P-Site Similarity: 100 100 33.3 92.8 N.A. 100 100 N.A. N.A. 0 0 35.7 N.A. 20 40 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 42 0 0 9 0 0 42 0 0 17 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 42 9 0 0 0 0 0 9 0 0 % D
% Glu: 0 0 0 0 0 9 0 9 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 17 0 0 0 0 0 0 0 0 0 0 0 9 9 % G
% His: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 9 9 17 9 9 0 0 9 9 0 42 50 42 % L
% Met: 0 50 0 0 0 0 0 0 0 0 0 0 17 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 50 0 42 0 0 42 42 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 42 0 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 9 9 9 9 9 9 9 42 25 9 9 50 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 17 0 0 0 9 0 0 9 % T
% Val: 0 0 0 9 0 0 9 0 0 0 0 0 0 9 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _