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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZD5 All Species: 35.45
Human Site: Y98 Identified Species: 70.91
UniProt: Q13467 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13467 NP_003459.2 585 64507 Y98 T P I C L P D Y H K P L P P C
Chimpanzee Pan troglodytes XP_526008 585 64475 Y98 T P I C L P D Y H K P L P P C
Rhesus Macaque Macaca mulatta XP_001096837 635 68033 Y100 T P I C L E D Y K K P L P P C
Dog Lupus familis XP_545614 589 64543 Y98 T P I C L P D Y H K P L P P C
Cat Felis silvestris
Mouse Mus musculus Q9EQD0 585 64119 Y98 T P I C L P D Y H K P L P P C
Rat Rattus norvegicus Q8CHL0 585 64093 Y98 T P I C L P D Y H K P L P P C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9IA06 523 59263 S52 P L V K V Q C S L E L K F F L
Frog Xenopus laevis P58421 559 63500 S88 D L K F F L C S M Y T P I C L
Zebra Danio Brachydanio rerio NP_571209 592 66471 Y110 T P I C L Q D Y K K P L P P C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVX3 694 75433 Y129 T P I C L E D Y H K P L P V C
Honey Bee Apis mellifera XP_397259 711 74000 Y163 T P I C L P E Y T K P L P A C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188449 555 62346 S84 P L V E I Q C S P D L K F F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 60.9 96.2 N.A. 96.2 96.4 N.A. N.A. 45.2 73.3 71.1 N.A. 50.8 48.9 N.A. 61.3
Protein Similarity: 100 99.6 69.1 96.7 N.A. 97.2 97.6 N.A. N.A. 58.9 81.1 78.5 N.A. 60.9 60.2 N.A. 72.3
P-Site Identity: 100 100 86.6 100 N.A. 100 100 N.A. N.A. 0 0 86.6 N.A. 86.6 80 N.A. 0
P-Site Similarity: 100 100 86.6 100 N.A. 100 100 N.A. N.A. 20 0 86.6 N.A. 86.6 86.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 75 0 0 25 0 0 0 0 0 0 9 75 % C
% Asp: 9 0 0 0 0 0 67 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 9 0 17 9 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 9 9 0 0 0 0 0 0 0 17 17 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % H
% Ile: 0 0 75 0 9 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 9 9 0 0 0 0 17 75 0 17 0 0 0 % K
% Leu: 0 25 0 0 75 9 0 0 9 0 17 75 0 0 25 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 17 75 0 0 0 50 0 0 9 0 75 9 75 59 0 % P
% Gln: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % S
% Thr: 75 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % T
% Val: 0 0 17 0 9 0 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _