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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFATC2
All Species:
22.73
Human Site:
Y294
Identified Species:
55.56
UniProt:
Q13469
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13469
NP_036472.2
925
100146
Y294
D
H
G
S
P
A
G
Y
P
P
V
A
G
S
A
Chimpanzee
Pan troglodytes
XP_525356
925
100057
Y294
D
H
G
A
P
A
G
Y
P
P
V
A
G
S
A
Rhesus Macaque
Macaca mulatta
XP_001099268
1047
113838
Y414
D
H
G
A
P
A
G
Y
P
P
V
A
G
S
A
Dog
Lupus familis
XP_543054
1113
119787
Y482
D
D
G
A
P
A
G
Y
P
P
A
A
G
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q60591
927
100060
Y296
D
D
S
I
P
A
G
Y
P
P
T
A
G
S
A
Rat
Rattus norvegicus
NP_001101275
931
100268
Y296
D
D
G
I
P
A
G
Y
P
P
T
A
G
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509026
936
102678
T296
R
E
D
G
S
S
V
T
F
T
Q
L
P
N
S
Chicken
Gallus gallus
XP_417509
953
104065
Y297
E
D
S
S
T
V
T
Y
T
Q
L
S
S
A
P
Frog
Xenopus laevis
NP_001085919
704
78205
G84
P
S
S
S
H
L
P
G
Y
G
G
N
L
D
S
Zebra Danio
Brachydanio rerio
NP_001038624
867
94251
E247
S
P
R
L
S
V
T
E
D
S
W
L
P
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
84.8
78.4
N.A.
89.7
90.1
N.A.
78.7
74.4
34.2
38
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
85.8
79.1
N.A.
92.7
92.8
N.A.
85.9
81.5
44.3
51.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
80
N.A.
73.3
80
N.A.
0
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
80
N.A.
20
40
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
30
0
60
0
0
0
0
10
60
0
10
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
40
10
0
0
0
0
0
10
0
0
0
0
10
0
% D
% Glu:
10
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
50
10
0
0
60
10
0
10
10
0
60
0
0
% G
% His:
0
30
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
0
0
0
0
10
20
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
20
0
% N
% Pro:
10
10
0
0
60
0
10
0
60
60
0
0
20
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
30
30
20
10
0
0
0
10
0
10
10
60
20
% S
% Thr:
0
0
0
0
10
0
20
10
10
10
20
0
0
0
10
% T
% Val:
0
0
0
0
0
20
10
0
0
0
30
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _