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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL18R1
All Species:
13.03
Human Site:
S494
Identified Species:
35.83
UniProt:
Q13478
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13478
NP_003846.1
541
62304
S494
Q
S
L
K
L
L
K
S
H
R
V
L
K
W
K
Chimpanzee
Pan troglodytes
XP_515669
521
59923
S474
Q
S
L
K
L
L
K
S
H
R
V
L
K
W
K
Rhesus Macaque
Macaca mulatta
P59822
570
65375
V520
E
L
K
R
A
K
T
V
L
T
V
I
K
W
K
Dog
Lupus familis
XP_854199
578
66569
S531
Q
S
L
K
L
L
K
S
H
R
V
L
K
W
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61098
537
61582
S491
P
S
L
K
L
L
K
S
Y
R
V
L
K
W
R
Rat
Rattus norvegicus
P59824
696
79753
L533
A
L
K
H
T
I
K
L
L
T
V
I
K
W
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514601
573
66108
Q507
E
S
I
Q
F
I
K
Q
K
H
G
V
L
R
W
Chicken
Gallus gallus
NP_001138697
510
59037
E464
D
R
A
I
Y
E
L
E
S
G
L
H
K
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B6ZK77
700
80295
L533
A
L
K
H
T
I
K
L
L
T
V
I
R
W
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
29.8
68.5
N.A.
64.3
26.2
N.A.
29.6
39.5
N.A.
24.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.1
47.1
77.6
N.A.
75.4
42.3
N.A.
48.3
57.1
N.A.
42.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
93.3
N.A.
80
26.6
N.A.
13.3
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
93.3
N.A.
93.3
40
N.A.
46.6
13.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
12
0
12
0
0
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
23
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% G
% His:
0
0
0
23
0
0
0
0
34
12
0
12
0
0
12
% H
% Ile:
0
0
12
12
0
34
0
0
0
0
0
34
0
0
0
% I
% Lys:
0
0
34
45
0
12
78
0
12
0
0
0
78
0
34
% K
% Leu:
0
34
45
0
45
45
12
23
34
0
12
45
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
34
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
12
0
0
0
0
0
45
0
0
12
12
12
% R
% Ser:
0
56
0
0
0
0
0
45
12
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
23
0
12
0
0
34
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
78
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
78
12
% W
% Tyr:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _