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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAB1
All Species:
26.97
Human Site:
Y373
Identified Species:
65.93
UniProt:
Q13480
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13480
NP_002030.2
694
76616
Y373
A
S
D
T
D
S
S
Y
C
I
P
T
A
G
M
Chimpanzee
Pan troglodytes
XP_517458
724
80051
Y373
A
S
D
T
D
S
S
Y
C
I
P
T
A
G
M
Rhesus Macaque
Macaca mulatta
XP_001093044
724
80118
Y373
A
S
D
T
D
N
S
Y
C
I
P
T
A
G
M
Dog
Lupus familis
XP_540929
719
79343
Y368
A
S
D
T
D
S
S
Y
C
I
P
T
A
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY0
695
76794
C374
S
D
T
D
S
S
Y
C
I
P
P
P
A
G
M
Rat
Rattus norvegicus
Q9EQH1
665
73310
E374
Q
Q
K
P
P
I
G
E
N
S
R
S
V
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513247
815
89872
Y464
A
S
D
T
D
N
S
Y
C
I
P
T
A
G
V
Chicken
Gallus gallus
XP_420422
691
76488
Y370
A
S
D
T
D
S
S
Y
C
I
P
T
A
G
I
Frog
Xenopus laevis
NP_001089201
691
76011
Y369
V
S
E
T
D
S
N
Y
C
V
P
T
S
G
M
Zebra Danio
Brachydanio rerio
XP_692935
666
73590
R373
S
T
A
S
V
I
P
R
R
N
T
L
P
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
94.8
90.2
N.A.
90.2
38.6
N.A.
76.9
88
75.5
40.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.5
95.1
92.3
N.A.
93.8
55.9
N.A.
80.6
92.5
85.4
56.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
33.3
0
N.A.
86.6
93.3
66.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
6.6
N.A.
100
100
93.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
10
0
0
0
0
0
0
0
0
0
70
20
10
% A
% Cys:
0
0
0
0
0
0
0
10
70
0
0
0
0
0
0
% C
% Asp:
0
10
60
10
70
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
80
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
20
0
0
10
60
0
0
0
0
10
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% M
% Asn:
0
0
0
0
0
20
10
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
10
0
0
10
80
10
10
0
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% R
% Ser:
20
70
0
10
10
60
60
0
0
10
0
10
10
0
0
% S
% Thr:
0
10
10
70
0
0
0
0
0
0
10
70
0
0
0
% T
% Val:
10
0
0
0
10
0
0
0
0
10
0
0
10
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _