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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TCIRG1 All Species: 13.64
Human Site: S149 Identified Species: 25
UniProt: Q13488 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13488 NP_006010.2 830 92968 S149 A A H T D G A S E R T P L L Q
Chimpanzee Pan troglodytes XP_522295 816 91321 S135 A A H T D G A S E R T P L L Q
Rhesus Macaque Macaca mulatta XP_001103418 830 92728 S149 A A H T D G T S E R M P L L Q
Dog Lupus familis XP_540812 830 93052 S149 A P H A D G L S E R S P L L Q
Cat Felis silvestris
Mouse Mus musculus P15920 856 98127 L160 P A L E N D S L L D Y S C M Q
Rat Rattus norvegicus P25286 838 96309 E149 M A D P D L L E E S S S L L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507655 845 96915 L143 S Y E E F P S L E K D S L V D
Chicken Gallus gallus Q9I8D0 838 95966 E149 M A D P D L L E E S S S L L E
Frog Xenopus laevis Q8AVM5 831 95538 E149 M A D P D L L E E S S T L L E
Zebra Danio Brachydanio rerio NP_998234 822 93457 S121 R N R D S L R S Q Y T Q L C Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30628 905 103383 H156 T F F E E V D H D R W R I L E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32563 840 95510 N185 A A I G A S V N Y V T G V I A
Red Bread Mold Neurospora crassa Q01290 856 97974 A165 A S T D N D D A P L L Q D V E
Conservation
Percent
Protein Identity: 100 98 96.1 86 N.A. 50.5 47.2 N.A. 50.4 47.8 48.9 57.9 N.A. N.A. N.A. 38.9 N.A.
Protein Similarity: 100 98.1 97.2 90.9 N.A. 66.4 64.9 N.A. 67 65.1 65.8 70.5 N.A. N.A. N.A. 56.7 N.A.
P-Site Identity: 100 100 86.6 73.3 N.A. 13.3 33.3 N.A. 13.3 33.3 33.3 26.6 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 100 86.6 80 N.A. 33.3 46.6 N.A. 40 46.6 46.6 33.3 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.9 36.6
Protein Similarity: N.A. N.A. N.A. N.A. 53.5 54
P-Site Identity: N.A. N.A. N.A. N.A. 20 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 62 0 8 8 0 16 8 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % C
% Asp: 0 0 24 16 54 16 16 0 8 8 8 0 8 0 8 % D
% Glu: 0 0 8 24 8 0 0 24 62 0 0 0 0 0 39 % E
% Phe: 0 8 8 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 31 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 31 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 8 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 31 31 16 8 8 8 0 70 62 0 % L
% Met: 24 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % M
% Asn: 0 8 0 0 16 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 24 0 8 0 0 8 0 0 31 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 16 0 0 47 % Q
% Arg: 8 0 8 0 0 0 8 0 0 39 0 8 0 0 0 % R
% Ser: 8 8 0 0 8 8 16 39 0 24 31 31 0 0 0 % S
% Thr: 8 0 8 24 0 0 8 0 0 0 31 8 0 0 0 % T
% Val: 0 0 0 0 0 8 8 0 0 8 0 0 8 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 8 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _