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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCIRG1
All Species:
19.39
Human Site:
S619
Identified Species:
35.56
UniProt:
Q13488
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13488
NP_006010.2
830
92968
S619
N
M
F
L
F
S
H
S
P
S
N
R
L
L
Y
Chimpanzee
Pan troglodytes
XP_522295
816
91321
S605
N
M
F
L
F
S
H
S
P
S
N
R
L
L
Y
Rhesus Macaque
Macaca mulatta
XP_001103418
830
92728
S619
N
M
F
L
F
S
H
S
P
T
N
R
P
L
Y
Dog
Lupus familis
XP_540812
830
93052
S619
N
M
F
L
F
S
R
S
P
T
N
R
L
L
F
Cat
Felis silvestris
Mouse
Mus musculus
P15920
856
98127
S636
N
M
F
L
F
P
T
S
K
T
H
G
L
Y
P
Rat
Rattus norvegicus
P25286
838
96309
P622
N
M
F
L
F
S
Y
P
E
S
G
N
A
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507655
845
96915
G625
N
M
F
L
F
P
L
G
G
S
S
E
L
Y
P
Chicken
Gallus gallus
Q9I8D0
838
95966
G622
N
M
F
L
F
S
Y
G
D
T
S
N
K
M
L
Frog
Xenopus laevis
Q8AVM5
831
95538
Q621
N
M
F
L
F
S
Y
Q
D
T
S
L
P
M
L
Zebra Danio
Brachydanio rerio
NP_998234
822
93457
N617
D
M
F
L
F
T
E
N
K
D
N
K
P
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30628
905
103383
R669
N
M
F
M
M
K
S
R
N
A
G
F
V
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32563
840
95510
T621
N
M
F
L
S
P
G
T
I
D
D
E
L
Y
P
Red Bread Mold
Neurospora crassa
Q01290
856
97974
T631
Y
M
F
L
Q
P
G
T
L
D
G
G
V
E
L
Conservation
Percent
Protein Identity:
100
98
96.1
86
N.A.
50.5
47.2
N.A.
50.4
47.8
48.9
57.9
N.A.
N.A.
N.A.
38.9
N.A.
Protein Similarity:
100
98.1
97.2
90.9
N.A.
66.4
64.9
N.A.
67
65.1
65.8
70.5
N.A.
N.A.
N.A.
56.7
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
46.6
46.6
N.A.
46.6
40
40
46.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
60
60
N.A.
53.3
66.6
66.6
73.3
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.9
36.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.5
54
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
16
24
8
0
0
8
8
% D
% Glu:
0
0
0
0
0
0
8
0
8
0
0
16
0
8
0
% E
% Phe:
0
0
100
0
77
0
0
0
0
0
0
8
0
0
8
% F
% Gly:
0
0
0
0
0
0
16
16
8
0
24
16
0
0
0
% G
% His:
0
0
0
0
0
0
24
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
16
0
0
8
8
0
0
% K
% Leu:
0
0
0
93
0
0
8
0
8
0
0
8
47
39
31
% L
% Met:
0
100
0
8
8
0
0
0
0
0
0
0
0
24
0
% M
% Asn:
85
0
0
0
0
0
0
8
8
0
39
16
0
0
0
% N
% Pro:
0
0
0
0
0
31
0
8
31
0
0
0
24
0
24
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
8
0
0
0
31
0
0
0
% R
% Ser:
0
0
0
0
8
54
8
39
0
31
24
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
8
16
0
39
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
24
0
0
0
0
0
0
24
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _