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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TCIRG1 All Species: 16.06
Human Site: T469 Identified Species: 29.44
UniProt: Q13488 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13488 NP_006010.2 830 92968 T469 N E C F S R A T S I F P S G W
Chimpanzee Pan troglodytes XP_522295 816 91321 T455 N E C F S R A T S I F P S G W
Rhesus Macaque Macaca mulatta XP_001103418 830 92728 T469 N E C F S R A T S I F P S G W
Dog Lupus familis XP_540812 830 93052 T469 N E C F S R A T T I F S S G W
Cat Felis silvestris
Mouse Mus musculus P15920 856 98127 S486 F G S G W N V S A M Y S S S H
Rat Rattus norvegicus P25286 838 96309 L472 N D C F S K S L N I F G S S W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507655 845 96915 S475 F G S K W N V S A M Y V P A K
Chicken Gallus gallus Q9I8D0 838 95966 L472 N D C F S K S L N M F G S S W
Frog Xenopus laevis Q8AVM5 831 95538 A471 Y N D C F S K A L N L F G S S
Zebra Danio Brachydanio rerio NP_998234 822 93457 L467 N E C F S K G L S T F S S G W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30628 905 103383 I508 N D V F S K S I N T F G S S W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32563 840 95510 M487 N D I F S K T M T I F K S G W
Red Bread Mold Neurospora crassa Q01290 856 97974 M491 N D V F S K S M T L F D S Q W
Conservation
Percent
Protein Identity: 100 98 96.1 86 N.A. 50.5 47.2 N.A. 50.4 47.8 48.9 57.9 N.A. N.A. N.A. 38.9 N.A.
Protein Similarity: 100 98.1 97.2 90.9 N.A. 66.4 64.9 N.A. 67 65.1 65.8 70.5 N.A. N.A. N.A. 56.7 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 6.6 53.3 N.A. 0 46.6 0 66.6 N.A. N.A. N.A. 40 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 33.3 80 N.A. 26.6 80 0 73.3 N.A. N.A. N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.9 36.6
Protein Similarity: N.A. N.A. N.A. N.A. 53.5 54
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 40
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 31 8 16 0 0 0 0 8 0 % A
% Cys: 0 0 54 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 39 8 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 39 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 16 0 0 77 8 0 0 0 0 0 77 8 0 0 0 % F
% Gly: 0 16 0 8 0 0 8 0 0 0 0 24 8 47 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 8 0 0 0 0 8 0 47 0 0 0 0 0 % I
% Lys: 0 0 0 8 0 47 8 0 0 0 0 8 0 0 8 % K
% Leu: 0 0 0 0 0 0 0 24 8 8 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 16 0 24 0 0 0 0 0 % M
% Asn: 77 8 0 0 0 16 0 0 24 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 24 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 31 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 16 0 77 8 31 16 31 0 0 24 85 39 8 % S
% Thr: 0 0 0 0 0 0 8 31 24 16 0 0 0 0 0 % T
% Val: 0 0 16 0 0 0 16 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 16 0 0 0 0 0 0 0 0 0 77 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _