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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BIRC2
All Species:
19.39
Human Site:
T500
Identified Species:
38.79
UniProt:
Q13490
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13490
NP_001157.1
618
69900
T500
H
D
I
I
K
Q
K
T
Q
I
P
L
Q
A
R
Chimpanzee
Pan troglodytes
Q95M72
236
27118
V128
M
G
F
D
F
K
D
V
K
K
I
M
E
E
R
Rhesus Macaque
Macaca mulatta
XP_001097089
618
69923
T500
H
D
I
I
K
Q
K
T
Q
I
P
L
Q
A
R
Dog
Lupus familis
XP_538165
615
69039
I498
N
P
M
L
Q
E
A
I
R
M
G
F
S
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q62210
612
69658
T494
H
D
I
I
R
Q
K
T
Q
I
P
L
Q
A
R
Rat
Rattus norvegicus
Q9R0I6
496
56054
I388
M
G
F
N
F
K
D
I
K
K
T
M
E
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509526
607
68021
T489
R
D
V
I
K
Q
K
T
Q
T
S
L
Q
A
R
Chicken
Gallus gallus
Q90660
611
68991
T493
H
D
V
I
K
Q
T
T
Q
T
P
S
Q
A
R
Frog
Xenopus laevis
A5D8Q0
488
55110
P380
Y
A
Q
Q
M
G
F
P
L
E
E
I
K
K
V
Zebra Danio
Brachydanio rerio
XP_002666015
647
72165
T529
Y
D
S
I
R
N
C
T
S
V
K
Q
Q
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24307
498
54520
T390
I
E
P
C
Q
A
T
T
S
K
A
A
S
V
P
Honey Bee
Apis mellifera
XP_396819
518
59795
K410
Q
I
M
E
K
S
T
K
E
Q
T
N
N
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20
98.3
21.8
N.A.
83.6
29.7
N.A.
74.9
68.2
33.5
55
N.A.
30.7
26.3
N.A.
N.A.
Protein Similarity:
100
28.3
99.6
39.1
N.A.
90.9
45.7
N.A.
85.5
81.3
48.5
71.4
N.A.
47.7
43.6
N.A.
N.A.
P-Site Identity:
100
6.6
100
0
N.A.
93.3
0
N.A.
73.3
73.3
0
26.6
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
33.3
100
53.3
N.A.
100
33.3
N.A.
80
80
20
46.6
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
9
0
0
0
9
9
0
42
0
% A
% Cys:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
0
9
0
0
17
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
9
0
9
0
0
9
9
9
0
17
17
9
% E
% Phe:
0
0
17
0
17
0
9
0
0
0
0
9
0
9
0
% F
% Gly:
0
17
0
0
0
9
0
0
0
0
9
0
0
0
9
% G
% His:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
25
50
0
0
0
17
0
25
9
9
0
9
0
% I
% Lys:
0
0
0
0
42
17
34
9
17
25
9
0
9
9
17
% K
% Leu:
0
0
0
9
0
0
0
0
9
0
0
34
0
0
0
% L
% Met:
17
0
17
0
9
0
0
0
0
9
0
17
0
0
0
% M
% Asn:
9
0
0
9
0
9
0
0
0
0
0
9
9
0
0
% N
% Pro:
0
9
9
0
0
0
0
9
0
0
34
0
0
0
9
% P
% Gln:
9
0
9
9
17
42
0
0
42
9
0
9
50
0
0
% Q
% Arg:
9
0
0
0
17
0
0
0
9
0
0
0
0
0
50
% R
% Ser:
0
0
9
0
0
9
0
0
17
0
9
9
17
0
0
% S
% Thr:
0
0
0
0
0
0
25
59
0
17
17
0
0
9
0
% T
% Val:
0
0
17
0
0
0
0
9
0
9
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _