KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PICALM
All Species:
29.7
Human Site:
S268
Identified Species:
54.44
UniProt:
Q13492
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13492
NP_001008660.1
652
70755
S268
R
G
D
I
P
D
L
S
Q
A
P
S
S
L
L
Chimpanzee
Pan troglodytes
XP_508908
793
85002
S416
R
G
D
I
P
D
L
S
Q
A
P
S
S
L
L
Rhesus Macaque
Macaca mulatta
XP_001085480
907
92424
T268
K
G
D
I
P
D
L
T
Q
A
P
S
S
L
M
Dog
Lupus familis
XP_858235
652
70722
S268
R
G
D
I
P
D
L
S
Q
A
P
S
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7M6Y3
660
71525
S268
R
G
D
I
P
D
L
S
Q
A
P
S
S
L
L
Rat
Rattus norvegicus
O55012
640
69267
S268
R
G
D
I
P
D
L
S
Q
A
P
S
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512668
642
69699
L260
P
S
S
L
L
D
A
L
E
Q
H
L
A
S
L
Chicken
Gallus gallus
XP_423671
651
70667
S268
R
G
D
I
P
D
L
S
Q
A
P
S
S
L
L
Frog
Xenopus laevis
NP_001085333
444
49230
N81
R
R
Y
S
R
Y
L
N
E
K
A
L
S
Y
R
Zebra Danio
Brachydanio rerio
NP_957221
589
63960
K226
L
E
K
Y
F
D
M
K
K
A
Q
C
K
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VI75
468
49849
T105
Y
L
A
S
S
N
S
T
F
N
L
S
S
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XZI6
586
64045
R223
L
L
F
R
D
L
I
R
L
F
A
C
Y
N
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53309
568
64310
S205
G
V
I
T
L
L
E
S
F
F
E
L
S
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
45
99.3
N.A.
96.5
96.1
N.A.
89.7
94.1
47
77.1
N.A.
41.4
N.A.
38.7
N.A.
Protein Similarity:
100
81.3
56
99.6
N.A.
97.7
96.9
N.A.
92.1
97.3
57.6
83.4
N.A.
54.2
N.A.
55.6
N.A.
P-Site Identity:
100
100
80
100
N.A.
100
100
N.A.
13.3
100
20
13.3
N.A.
20
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
100
33.3
26.6
N.A.
33.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
62
16
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% C
% Asp:
0
0
54
0
8
70
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
8
0
0
0
0
8
0
16
0
8
0
0
8
8
% E
% Phe:
0
0
8
0
8
0
0
0
16
16
0
0
0
8
0
% F
% Gly:
8
54
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
54
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
8
0
0
0
0
8
8
8
0
0
8
0
0
% K
% Leu:
16
16
0
8
16
16
62
8
8
0
8
24
0
54
62
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
8
0
8
0
0
0
8
0
% N
% Pro:
8
0
0
0
54
0
0
0
0
0
54
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
54
8
8
0
0
0
0
% Q
% Arg:
54
8
0
8
8
0
0
8
0
0
0
0
0
0
8
% R
% Ser:
0
8
8
16
8
0
8
54
0
0
0
62
77
8
0
% S
% Thr:
0
0
0
8
0
0
0
16
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
8
0
8
0
0
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _