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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PICALM
All Species:
28.79
Human Site:
S272
Identified Species:
52.78
UniProt:
Q13492
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13492
NP_001008660.1
652
70755
S272
P
D
L
S
Q
A
P
S
S
L
L
D
A
L
E
Chimpanzee
Pan troglodytes
XP_508908
793
85002
S420
P
D
L
S
Q
A
P
S
S
L
L
D
A
L
E
Rhesus Macaque
Macaca mulatta
XP_001085480
907
92424
S272
P
D
L
T
Q
A
P
S
S
L
M
E
T
L
E
Dog
Lupus familis
XP_858235
652
70722
S272
P
D
L
S
Q
A
P
S
S
L
L
D
A
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7M6Y3
660
71525
S272
P
D
L
S
Q
A
P
S
S
L
L
D
A
L
E
Rat
Rattus norvegicus
O55012
640
69267
S272
P
D
L
S
Q
A
P
S
S
L
L
D
A
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512668
642
69699
L264
L
D
A
L
E
Q
H
L
A
S
L
E
G
K
K
Chicken
Gallus gallus
XP_423671
651
70667
S272
P
D
L
S
Q
A
P
S
S
L
L
D
A
L
E
Frog
Xenopus laevis
NP_001085333
444
49230
L85
R
Y
L
N
E
K
A
L
S
Y
R
L
V
A
V
Zebra Danio
Brachydanio rerio
NP_957221
589
63960
C230
F
D
M
K
K
A
Q
C
K
E
G
L
D
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VI75
468
49849
S109
S
N
S
T
F
N
L
S
S
F
L
D
K
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XZI6
586
64045
C227
D
L
I
R
L
F
A
C
Y
N
D
G
I
I
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53309
568
64310
L209
L
L
E
S
F
F
E
L
S
I
E
H
A
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
45
99.3
N.A.
96.5
96.1
N.A.
89.7
94.1
47
77.1
N.A.
41.4
N.A.
38.7
N.A.
Protein Similarity:
100
81.3
56
99.6
N.A.
97.7
96.9
N.A.
92.1
97.3
57.6
83.4
N.A.
54.2
N.A.
55.6
N.A.
P-Site Identity:
100
100
73.3
100
N.A.
100
100
N.A.
13.3
100
13.3
13.3
N.A.
26.6
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
40
100
26.6
33.3
N.A.
40
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
62
16
0
8
0
0
0
54
8
0
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% C
% Asp:
8
70
0
0
0
0
0
0
0
0
8
54
8
0
0
% D
% Glu:
0
0
8
0
16
0
8
0
0
8
8
16
0
0
54
% E
% Phe:
8
0
0
0
16
16
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
8
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
8
0
0
8
16
0
% I
% Lys:
0
0
0
8
8
8
0
0
8
0
0
0
8
16
8
% K
% Leu:
16
16
62
8
8
0
8
24
0
54
62
16
0
54
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
8
0
8
0
0
0
8
0
0
0
0
8
% N
% Pro:
54
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
54
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% R
% Ser:
8
0
8
54
0
0
0
62
77
8
0
0
0
0
0
% S
% Thr:
0
0
0
16
0
0
0
0
0
0
0
0
8
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _