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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PICALM
All Species:
26.67
Human Site:
S297
Identified Species:
48.89
UniProt:
Q13492
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13492
NP_001008660.1
652
70755
S297
I
K
D
S
T
A
A
S
R
A
T
T
L
S
N
Chimpanzee
Pan troglodytes
XP_508908
793
85002
S445
I
K
D
S
T
A
A
S
R
A
T
T
L
S
N
Rhesus Macaque
Macaca mulatta
XP_001085480
907
92424
G297
P
G
N
N
E
G
S
G
A
P
S
P
L
S
K
Dog
Lupus familis
XP_858235
652
70722
S297
I
K
D
S
T
A
A
S
R
A
T
T
L
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q7M6Y3
660
71525
S297
I
K
D
S
T
A
A
S
R
A
T
T
L
S
N
Rat
Rattus norvegicus
O55012
640
69267
S297
I
K
D
S
T
A
A
S
R
A
T
T
L
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512668
642
69699
S289
T
T
L
S
N
A
V
S
S
L
A
S
T
G
L
Chicken
Gallus gallus
XP_423671
651
70667
S297
I
K
D
S
T
A
A
S
R
A
T
T
L
S
N
Frog
Xenopus laevis
NP_001085333
444
49230
T110
G
V
M
R
T
M
A
T
E
K
L
L
K
T
L
Zebra Danio
Brachydanio rerio
NP_957221
589
63960
E255
S
E
F
L
K
V
A
E
Q
V
G
I
D
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VI75
468
49849
S134
G
R
M
G
Y
D
M
S
P
F
I
R
R
Y
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XZI6
586
64045
D252
K
Q
C
R
D
A
L
D
T
Y
K
S
F
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53309
568
64310
Y234
M
T
E
Y
V
V
R
Y
L
K
I
G
K
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
45
99.3
N.A.
96.5
96.1
N.A.
89.7
94.1
47
77.1
N.A.
41.4
N.A.
38.7
N.A.
Protein Similarity:
100
81.3
56
99.6
N.A.
97.7
96.9
N.A.
92.1
97.3
57.6
83.4
N.A.
54.2
N.A.
55.6
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
20
100
13.3
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
26.6
100
26.6
20
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
62
62
0
8
47
8
0
0
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
47
0
8
8
0
8
0
0
0
0
8
0
0
% D
% Glu:
0
8
8
0
8
0
0
8
8
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
16
8
0
8
0
8
0
8
0
0
8
8
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
0
0
0
0
0
0
0
0
0
16
8
0
0
0
% I
% Lys:
8
47
0
0
8
0
0
0
0
16
8
0
16
0
8
% K
% Leu:
0
0
8
8
0
0
8
0
8
8
8
8
54
8
16
% L
% Met:
8
0
16
0
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
47
% N
% Pro:
8
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
16
0
0
8
0
47
0
0
8
8
8
0
% R
% Ser:
8
0
0
54
0
0
8
62
8
0
8
16
0
54
0
% S
% Thr:
8
16
0
0
54
0
0
8
8
0
47
47
8
8
8
% T
% Val:
0
8
0
0
8
16
8
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
8
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _