KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PICALM
All Species:
25.15
Human Site:
T464
Identified Species:
46.11
UniProt:
Q13492
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13492
NP_001008660.1
652
70755
T464
T
F
T
T
R
T
P
T
H
E
M
F
V
G
F
Chimpanzee
Pan troglodytes
XP_508908
793
85002
T605
T
F
T
T
R
T
P
T
H
E
M
F
V
G
F
Rhesus Macaque
Macaca mulatta
XP_001085480
907
92424
S681
G
G
S
F
M
A
P
S
P
S
P
V
T
P
A
Dog
Lupus familis
XP_858235
652
70722
T464
T
F
T
T
R
T
P
T
H
E
M
F
V
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q7M6Y3
660
71525
T464
T
F
T
T
R
T
P
T
H
E
M
F
V
G
F
Rat
Rattus norvegicus
O55012
640
69267
T452
S
S
D
V
S
T
F
T
T
R
T
P
T
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512668
642
69699
T446
T
F
A
C
R
T
P
T
H
E
M
F
V
G
F
Chicken
Gallus gallus
XP_423671
651
70667
T463
T
F
T
S
R
T
P
T
H
E
M
F
V
G
F
Frog
Xenopus laevis
NP_001085333
444
49230
T257
T
L
S
T
A
V
S
T
L
A
T
T
G
M
S
Zebra Danio
Brachydanio rerio
NP_957221
589
63960
Q402
L
D
L
Q
P
A
F
Q
P
S
L
P
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VI75
468
49849
L281
D
K
G
D
I
P
D
L
T
K
A
P
S
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XZI6
586
64045
Q399
S
S
A
A
P
A
P
Q
T
A
D
V
T
N
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53309
568
64310
Q381
P
F
L
I
P
Q
Q
Q
Q
Q
A
L
Q
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
45
99.3
N.A.
96.5
96.1
N.A.
89.7
94.1
47
77.1
N.A.
41.4
N.A.
38.7
N.A.
Protein Similarity:
100
81.3
56
99.6
N.A.
97.7
96.9
N.A.
92.1
97.3
57.6
83.4
N.A.
54.2
N.A.
55.6
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
13.3
N.A.
86.6
93.3
20
0
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
20
N.A.
86.6
100
26.6
13.3
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
8
24
0
0
0
16
16
0
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
0
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
47
0
0
0
0
8
% E
% Phe:
0
54
0
8
0
0
16
0
0
0
0
47
0
0
47
% F
% Gly:
8
8
8
0
0
0
0
0
0
0
0
0
8
47
0
% G
% His:
0
0
0
0
0
0
0
0
47
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
8
16
0
0
0
0
8
8
0
8
8
8
8
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
47
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
8
0
0
0
24
8
62
0
16
0
8
24
0
8
8
% P
% Gln:
0
0
0
8
0
8
8
24
8
8
0
0
8
0
0
% Q
% Arg:
0
0
0
0
47
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
16
16
16
8
8
0
8
8
0
16
0
0
8
16
16
% S
% Thr:
54
0
39
39
0
54
0
62
24
0
16
8
24
0
8
% T
% Val:
0
0
0
8
0
8
0
0
0
0
0
16
47
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _