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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SQSTM1 All Species: 6.97
Human Site: S266 Identified Species: 17.04
UniProt: Q13501 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13501 NP_001135771.1 440 47687 S266 V E H G G K R S R L T P V S P
Chimpanzee Pan troglodytes XP_518154 440 47713 S266 V E H G G K R S R L T P V S P
Rhesus Macaque Macaca mulatta XP_001102347 439 47572 R265 D V E H G G K R S R L T P A S
Dog Lupus familis XP_538580 688 72696 R346 E H G G K R S R L T P V S P G
Cat Felis silvestris
Mouse Mus musculus Q64337 442 48144 L268 H G G K R S R L T P T T P E S
Rat Rattus norvegicus O08623 439 47663 L265 H G G K R S R L T P T S A E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506086 492 54053 S318 S Q P S S R S S S D A Q G G S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P14199 599 65285 S390 G A S S A N Q S A V P S A A P
Honey Bee Apis mellifera XP_392222 399 45715 L225 N N F I D A L L E V H N V E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795534 414 45119 G236 P N F C G G G G G G H G R G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.7 49.7 N.A. 90.7 91.3 N.A. 59.9 N.A. N.A. N.A. N.A. 21.3 22.9 N.A. 30.6
Protein Similarity: 100 99.7 98.8 54.5 N.A. 94.3 94.5 N.A. 70.5 N.A. N.A. N.A. N.A. 35.2 43.4 N.A. 42.5
P-Site Identity: 100 100 6.6 6.6 N.A. 13.3 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 20 13.3 N.A. 13.3 13.3 N.A. 20 N.A. N.A. N.A. N.A. 33.3 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 10 0 0 10 0 10 0 20 20 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 10 20 10 0 0 0 0 0 10 0 0 0 0 30 0 % E
% Phe: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 20 30 30 40 20 10 10 10 10 0 10 10 20 10 % G
% His: 20 10 20 10 0 0 0 0 0 0 20 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 20 10 20 10 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 0 0 0 10 30 10 20 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 20 0 0 0 10 0 0 0 0 0 10 0 0 0 % N
% Pro: 10 0 10 0 0 0 0 0 0 20 20 20 20 10 30 % P
% Gln: 0 10 0 0 0 0 10 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 20 20 40 20 20 10 0 0 10 0 0 % R
% Ser: 10 0 10 20 10 20 20 40 20 0 0 20 10 20 50 % S
% Thr: 0 0 0 0 0 0 0 0 20 10 40 20 0 0 0 % T
% Val: 20 10 0 0 0 0 0 0 0 20 0 10 30 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _