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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SQSTM1 All Species: 21.82
Human Site: S366 Identified Species: 53.33
UniProt: Q13501 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13501 NP_001135771.1 440 47687 S366 P E S E G P S S L D P S Q E G
Chimpanzee Pan troglodytes XP_518154 440 47713 S366 P E S E G P S S L D P S Q E G
Rhesus Macaque Macaca mulatta XP_001102347 439 47572 S365 P E S E G P S S L D P S Q E G
Dog Lupus familis XP_538580 688 72696 S446 P E S E G P G S L G S S Q E G
Cat Felis silvestris
Mouse Mus musculus Q64337 442 48144 S368 P E S E G P S S L D P S Q E G
Rat Rattus norvegicus O08623 439 47663 S365 P E S E G P S S L D P S Q E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506086 492 54053 V418 E S E N P Y S V D P P Q E E G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P14199 599 65285 L490 P V R D F G Q L G E L L R Q H
Honey Bee Apis mellifera XP_392222 399 45715 K325 N E T N E K E K S S S T A P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795534 414 45119 D336 Q S P S G S D D A D W T L L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.7 49.7 N.A. 90.7 91.3 N.A. 59.9 N.A. N.A. N.A. N.A. 21.3 22.9 N.A. 30.6
Protein Similarity: 100 99.7 98.8 54.5 N.A. 94.3 94.5 N.A. 70.5 N.A. N.A. N.A. N.A. 35.2 43.4 N.A. 42.5
P-Site Identity: 100 100 100 80 N.A. 100 100 N.A. 26.6 N.A. N.A. N.A. N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 80 N.A. 100 100 N.A. 33.3 N.A. N.A. N.A. N.A. 33.3 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 10 10 10 60 0 0 0 0 0 % D
% Glu: 10 70 10 60 10 0 10 0 0 10 0 0 10 70 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 70 10 10 0 10 10 0 0 0 0 70 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 10 60 0 10 10 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 70 0 10 0 10 60 0 0 0 10 60 0 0 10 0 % P
% Gln: 10 0 0 0 0 0 10 0 0 0 0 10 60 10 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 20 60 10 0 10 60 60 10 10 20 60 0 0 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 20 0 0 0 % T
% Val: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _