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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED21
All Species:
30.91
Human Site:
S128
Identified Species:
52.31
UniProt:
Q13503
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13503
NP_004255.2
144
15564
S128
A
L
A
D
I
A
Q
S
Q
L
K
T
R
S
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099368
144
15505
S128
A
L
A
D
I
A
Q
S
Q
L
K
T
R
S
G
Dog
Lupus familis
XP_852318
144
15519
S128
A
L
A
D
I
A
Q
S
Q
L
K
T
R
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ39
144
15570
S128
A
L
A
D
I
A
Q
S
Q
L
K
T
R
S
V
Rat
Rattus norvegicus
NP_001101365
90
9661
S75
D
I
D
V
L
I
D
S
L
P
S
E
E
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505512
135
14409
Q120
L
A
D
I
A
Q
S
Q
L
K
T
R
S
G
P
Chicken
Gallus gallus
XP_416442
144
15564
S128
A
L
A
D
I
A
Q
S
Q
L
K
T
R
S
G
Frog
Xenopus laevis
NP_001085938
145
15874
S128
A
L
A
D
I
A
Q
S
Q
L
K
T
R
S
R
Zebra Danio
Brachydanio rerio
Q7ZTI5
145
15608
S128
A
L
A
D
I
A
Q
S
Q
L
R
T
R
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5P1
142
16051
A127
Q
Y
S
L
E
C
I
A
Q
A
Q
L
D
M
Q
Honey Bee
Apis mellifera
XP_396033
175
19345
S125
A
L
Q
D
I
A
Q
S
Q
L
D
M
Q
D
P
Nematode Worm
Caenorhab. elegans
Q6BER6
130
14117
K115
L
V
G
V
V
Q
K
K
L
A
E
I
S
K
T
Sea Urchin
Strong. purpuratus
XP_796120
177
18671
A127
A
L
A
E
I
A
D
A
Q
L
K
T
K
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47822
140
16053
L125
L
L
R
H
V
D
S
L
I
E
D
F
V
D
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
99.3
N.A.
97.9
60.4
N.A.
87.5
95.1
84.8
86.9
N.A.
53.4
48.5
36.8
50.8
Protein Similarity:
100
N.A.
100
100
N.A.
98.6
62.5
N.A.
92.3
97.2
92.4
93
N.A.
66.6
60.5
53.4
61.5
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
13.3
N.A.
0
100
93.3
93.3
N.A.
6.6
60
0
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
26.6
N.A.
0
100
93.3
100
N.A.
26.6
66.6
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
65
8
58
0
8
65
0
15
0
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
15
58
0
8
15
0
0
0
15
0
8
15
0
% D
% Glu:
0
0
0
8
8
0
0
0
0
8
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
43
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
65
8
8
0
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
8
0
8
50
0
8
8
0
% K
% Leu:
22
72
0
8
8
0
0
8
22
65
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
15
% P
% Gln:
8
0
8
0
0
15
58
8
72
0
8
0
8
0
8
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
8
8
50
0
8
% R
% Ser:
0
0
8
0
0
0
15
65
0
0
8
0
15
65
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
58
0
0
15
% T
% Val:
0
8
0
15
15
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _