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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED21
All Species:
27.27
Human Site:
S134
Identified Species:
46.15
UniProt:
Q13503
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13503
NP_004255.2
144
15564
S134
Q
S
Q
L
K
T
R
S
G
T
H
S
Q
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099368
144
15505
S134
Q
S
Q
L
K
T
R
S
G
S
H
S
Q
S
L
Dog
Lupus familis
XP_852318
144
15519
S134
Q
S
Q
L
K
T
R
S
G
T
H
S
Q
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ39
144
15570
S134
Q
S
Q
L
K
T
R
S
V
T
H
S
H
S
L
Rat
Rattus norvegicus
NP_001101365
90
9661
S81
D
S
L
P
S
E
E
S
T
A
A
L
Q
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505512
135
14409
G126
S
Q
L
K
T
R
S
G
P
H
S
H
A
V
P
Chicken
Gallus gallus
XP_416442
144
15564
S134
Q
S
Q
L
K
T
R
S
G
A
H
S
Q
P
L
Frog
Xenopus laevis
NP_001085938
145
15874
S134
Q
S
Q
L
K
T
R
S
R
A
H
T
Q
Q
P
Zebra Danio
Brachydanio rerio
Q7ZTI5
145
15608
S134
Q
S
Q
L
R
T
R
S
G
A
P
S
Q
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5P1
142
16051
M133
I
A
Q
A
Q
L
D
M
Q
I
T
L
K
H
D
Honey Bee
Apis mellifera
XP_396033
175
19345
D131
Q
S
Q
L
D
M
Q
D
P
A
S
T
S
N
I
Nematode Worm
Caenorhab. elegans
Q6BER6
130
14117
K121
K
K
L
A
E
I
S
K
T
Q
M
S
S
R
P
Sea Urchin
Strong. purpuratus
XP_796120
177
18671
S133
D
A
Q
L
K
T
K
S
S
S
S
L
A
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47822
140
16053
D131
S
L
I
E
D
F
V
D
G
I
A
N
S
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
99.3
N.A.
97.9
60.4
N.A.
87.5
95.1
84.8
86.9
N.A.
53.4
48.5
36.8
50.8
Protein Similarity:
100
N.A.
100
100
N.A.
98.6
62.5
N.A.
92.3
97.2
92.4
93
N.A.
66.6
60.5
53.4
61.5
P-Site Identity:
100
N.A.
93.3
100
N.A.
86.6
20
N.A.
0
86.6
66.6
66.6
N.A.
6.6
26.6
6.6
33.3
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
20
N.A.
0
86.6
73.3
73.3
N.A.
26.6
53.3
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
15
0
0
0
0
0
36
15
0
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
15
0
8
15
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
8
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
43
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
43
8
8
8
0
% H
% Ile:
8
0
8
0
0
8
0
0
0
15
0
0
0
0
8
% I
% Lys:
8
8
0
8
50
0
8
8
0
0
0
0
8
8
15
% K
% Leu:
0
8
22
65
0
8
0
0
0
0
0
22
0
0
36
% L
% Met:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
15
0
8
0
0
8
22
% P
% Gln:
58
8
72
0
8
0
8
0
8
8
0
0
50
15
0
% Q
% Arg:
0
0
0
0
8
8
50
0
8
0
0
0
0
8
0
% R
% Ser:
15
65
0
0
8
0
15
65
8
15
22
50
22
29
8
% S
% Thr:
0
0
0
0
8
58
0
0
15
22
8
15
0
0
8
% T
% Val:
0
0
0
0
0
0
8
0
8
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _