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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED21
All Species:
22.94
Human Site:
S138
Identified Species:
38.83
UniProt:
Q13503
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13503
NP_004255.2
144
15564
S138
K
T
R
S
G
T
H
S
Q
S
L
P
D
S
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099368
144
15505
S138
K
T
R
S
G
S
H
S
Q
S
L
P
D
S
_
Dog
Lupus familis
XP_852318
144
15519
S138
K
T
R
S
G
T
H
S
Q
S
L
P
D
S
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ39
144
15570
S138
K
T
R
S
V
T
H
S
H
S
L
P
D
S
_
Rat
Rattus norvegicus
NP_001101365
90
9661
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505512
135
14409
Chicken
Gallus gallus
XP_416442
144
15564
S138
K
T
R
S
G
A
H
S
Q
P
L
P
D
S
_
Frog
Xenopus laevis
NP_001085938
145
15874
T138
K
T
R
S
R
A
H
T
Q
Q
P
L
P
E
S
Zebra Danio
Brachydanio rerio
Q7ZTI5
145
15608
S138
R
T
R
S
G
A
P
S
Q
Q
T
P
P
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5P1
142
16051
Honey Bee
Apis mellifera
XP_396033
175
19345
T135
D
M
Q
D
P
A
S
T
S
N
I
N
L
N
T
Nematode Worm
Caenorhab. elegans
Q6BER6
130
14117
Sea Urchin
Strong. purpuratus
XP_796120
177
18671
L137
K
T
K
S
S
S
S
L
A
A
S
L
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47822
140
16053
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
99.3
N.A.
97.9
60.4
N.A.
87.5
95.1
84.8
86.9
N.A.
53.4
48.5
36.8
50.8
Protein Similarity:
100
N.A.
100
100
N.A.
98.6
62.5
N.A.
92.3
97.2
92.4
93
N.A.
66.6
60.5
53.4
61.5
P-Site Identity:
100
N.A.
92.8
100
N.A.
85.7
0
N.A.
0
85.7
40
46.6
N.A.
0
0
0
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
85.7
0
N.A.
0
85.7
46.6
53.3
N.A.
0
33.3
0
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
29
0
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
0
0
0
36
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
36
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
43
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
50
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
36
15
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% N
% Pro:
0
0
0
0
8
0
8
0
0
8
8
43
15
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
43
15
0
0
0
0
0
% Q
% Arg:
8
0
50
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
58
8
15
15
43
8
29
8
0
8
43
22
% S
% Thr:
0
58
0
0
0
22
0
15
0
0
8
0
0
0
8
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% _