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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTX1
All Species:
5.76
Human Site:
S199
Identified Species:
11.52
UniProt:
Q13505
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13505
NP_002446.2
466
51477
S199
S
N
P
W
Q
S
P
S
G
T
L
P
A
L
R
Chimpanzee
Pan troglodytes
XP_001137204
312
35075
I55
G
S
R
G
D
V
P
I
L
T
T
E
D
D
M
Rhesus Macaque
Macaca mulatta
XP_001104637
310
34847
P52
P
G
G
D
G
D
V
P
I
L
T
T
E
D
N
Dog
Lupus familis
XP_537253
462
50359
S195
T
N
P
W
Q
S
P
S
G
T
L
P
A
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P47802
317
35605
D60
L
P
A
L
R
T
S
D
G
K
V
I
T
V
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510944
299
33244
I42
V
V
S
Q
P
A
K
I
L
N
F
L
R
K
Q
Chicken
Gallus gallus
NP_001072951
247
27799
Frog
Xenopus laevis
Q3KPT9
309
34626
P51
A
S
P
K
G
T
V
P
F
L
T
S
A
G
E
Zebra Danio
Brachydanio rerio
Q4VBW0
313
35209
I56
I
T
A
S
V
P
Q
I
H
Y
E
G
T
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624291
292
33701
P35
Y
A
K
F
N
G
I
P
L
K
I
N
S
A
G
Nematode Worm
Caenorhab. elegans
O45503
312
35301
T55
E
L
P
M
V
A
Q
T
E
G
E
A
K
P
V
Sea Urchin
Strong. purpuratus
XP_790728
319
36709
T62
V
F
Y
S
D
G
R
T
L
K
S
A
D
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.8
29.8
79.8
N.A.
62
N.A.
N.A.
27
28.3
31.7
30
N.A.
N.A.
25.9
24.8
29.1
Protein Similarity:
100
44.2
44.2
84.5
N.A.
64.5
N.A.
N.A.
39
39.4
42.7
42.2
N.A.
N.A.
38.8
36.4
43.3
P-Site Identity:
100
13.3
0
93.3
N.A.
6.6
N.A.
N.A.
0
0
13.3
0
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
20
0
100
N.A.
33.3
N.A.
N.A.
13.3
0
33.3
0
N.A.
N.A.
20
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
0
0
17
0
0
0
0
0
17
25
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
17
9
0
9
0
0
0
0
17
17
0
% D
% Glu:
9
0
0
0
0
0
0
0
9
0
17
9
9
0
9
% E
% Phe:
0
9
0
9
0
0
0
0
9
0
9
0
0
0
0
% F
% Gly:
9
9
9
9
17
17
0
0
25
9
0
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
9
25
9
0
9
9
0
0
9
% I
% Lys:
0
0
9
9
0
0
9
0
0
25
0
0
9
9
0
% K
% Leu:
9
9
0
9
0
0
0
0
34
17
17
9
0
17
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
17
0
0
9
0
0
0
0
9
0
9
0
0
9
% N
% Pro:
9
9
34
0
9
9
25
25
0
0
0
17
0
9
9
% P
% Gln:
0
0
0
9
17
0
17
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
9
0
9
0
9
0
0
0
0
0
9
0
17
% R
% Ser:
9
17
9
17
0
17
9
17
0
0
9
9
9
9
0
% S
% Thr:
9
9
0
0
0
17
0
17
0
25
25
9
17
9
0
% T
% Val:
17
9
0
0
17
9
17
0
0
0
9
0
0
9
17
% V
% Trp:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _