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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRPC3 All Species: 27.27
Human Site: T412 Identified Species: 66.67
UniProt: Q13507 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13507 NP_001124170.1 848 97355 T412 S D R F E G I T T L P N I T V
Chimpanzee Pan troglodytes XP_001153548 848 97349 T412 S D R F E G I T T L P N I T V
Rhesus Macaque Macaca mulatta XP_001111979 862 99426 K414 S D R F E G V K T L P N E T F
Dog Lupus familis XP_540964 1011 114713 T575 S D R F E G I T T L P N I T V
Cat Felis silvestris
Mouse Mus musculus Q9QZC1 836 95653 T400 S D R F E G I T T L P N I T V
Rat Rattus norvegicus Q9JMI9 836 95664 T400 S D R F E G I T T L P N I T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513859 925 106258 T489 S D R F E G I T T L P N I T V
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002664340 902 103693 T464 S D R F E G I T T L P N V T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJJ7 1128 127091 F385 E T F I G G W F F A D S S G M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34586 1027 118084 E411 L L T W A T F E D Y R Y E K G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 79.8 83 N.A. 95 95 N.A. 88.4 N.A. N.A. 82 N.A. 25.7 N.A. 34.4 N.A.
Protein Similarity: 100 99.8 88.8 83.3 N.A. 96.6 96.5 N.A. 90 N.A. N.A. 88 N.A. 43.7 N.A. 52.8 N.A.
P-Site Identity: 100 100 73.3 100 N.A. 100 100 N.A. 100 N.A. N.A. 93.3 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 100 80 100 N.A. 100 100 N.A. 100 N.A. N.A. 100 N.A. 20 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 80 0 0 0 0 0 0 10 0 10 0 0 0 0 % D
% Glu: 10 0 0 0 80 0 0 10 0 0 0 0 20 0 0 % E
% Phe: 0 0 10 80 0 0 10 10 10 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 10 90 0 0 0 0 0 0 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 70 0 0 0 0 0 60 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % K
% Leu: 10 10 0 0 0 0 0 0 0 80 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 80 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 80 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 80 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % S
% Thr: 0 10 10 0 0 10 0 70 80 0 0 0 0 80 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 70 % V
% Trp: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _