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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBB3
All Species:
9.09
Human Site:
S444
Identified Species:
20
UniProt:
Q13509
Number Species:
10
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13509
NP_006077.2
450
50433
S444
Y
E
D
D
E
E
E
S
E
A
Q
G
P
K
_
Chimpanzee
Pan troglodytes
Q8WP14
444
49773
D435
A
T
A
E
E
E
E
D
E
E
Y
A
E
E
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860049
456
51071
S450
Y
E
D
D
E
E
E
S
E
A
Q
G
P
K
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERD7
450
50400
S444
Y
E
D
D
D
E
E
S
E
A
Q
G
P
K
_
Rat
Rattus norvegicus
Q6P9T8
445
49782
E435
A
T
A
E
E
E
G
E
F
E
E
E
A
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09652
449
50402
Frog
Xenopus laevis
P30883
445
49797
E435
A
T
A
E
E
E
G
E
F
E
E
G
E
E
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24560
447
50129
Honey Bee
Apis mellifera
XP_392313
447
50157
Nematode Worm
Caenorhab. elegans
P41937
444
49782
E435
A
T
A
D
D
E
G
E
F
D
E
H
D
Q
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P18025
446
49944
E437
A
D
E
E
G
E
Y
E
D
E
E
E
G
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
N.A.
98.6
N.A.
99.7
91.5
N.A.
N.A.
99.3
91.7
N.A.
N.A.
90.4
90.6
88.6
N.A.
Protein Similarity:
100
91.5
N.A.
98.6
N.A.
100
95.3
N.A.
N.A.
99.3
95.5
N.A.
N.A.
95.1
95.5
94.8
N.A.
P-Site Identity:
100
26.6
N.A.
100
N.A.
92.8
13.3
N.A.
N.A.
0
20
N.A.
N.A.
0
0
13.3
N.A.
P-Site Similarity:
100
40
N.A.
100
N.A.
100
33.3
N.A.
N.A.
0
40
N.A.
N.A.
0
0
33.3
N.A.
Percent
Protein Identity:
N.A.
82.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
91.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
37
0
0
0
0
0
0
28
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
28
37
19
0
0
10
10
10
0
0
10
10
10
% D
% Glu:
0
28
10
37
46
73
37
37
37
37
37
19
19
28
28
% E
% Phe:
0
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
28
0
0
0
0
37
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
28
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
28
0
0
0
0
0
0
0
% S
% Thr:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
28
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
28
% _