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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASAH1 All Species: 33.03
Human Site: S345 Identified Species: 72.67
UniProt: Q13510 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13510 NP_001120977.1 395 44660 S345 K M C L N R T S Q E N I S F E
Chimpanzee Pan troglodytes A5A6P2 395 44678 S345 K M C L N R T S Q E N I S F E
Rhesus Macaque Macaca mulatta XP_001098342 395 44787 T345 K M C L N R T T Q E N I S F E
Dog Lupus familis XP_540012 386 44148 T336 K M C L N Q T T Q E N I S F A
Cat Felis silvestris
Mouse Mus musculus Q9WV54 394 44651 T344 K K C L N H T T Q K N L S F A
Rat Rattus norvegicus Q6P7S1 394 44425 T344 K K C L N H T T Q K N L S F A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521781 260 29621 I214 N R T T Q G R I S F A S V Y D
Chicken Gallus gallus
Frog Xenopus laevis NP_001087503 395 44309 S345 M K C M R R T S Q Q N I S F G
Zebra Danio Brachydanio rerio NP_956871 395 44662 T345 M K C M N Q T T Q T N I S V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45686 393 44805 T343 F R C M D K L T Q K N V G F E
Sea Urchin Strong. purpuratus XP_784832 392 43432 T342 T K C M N T M T Q A N V G L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 93.9 79.7 N.A. 79.2 82.5 N.A. 49.8 N.A. 61.7 59.7 N.A. N.A. N.A. 38.7 46.3
Protein Similarity: 100 99.2 97.7 89.1 N.A. 91.6 91.6 N.A. 58.7 N.A. 79.4 80.5 N.A. N.A. N.A. 62 65.5
P-Site Identity: 100 100 93.3 80 N.A. 60 60 N.A. 0 N.A. 60 46.6 N.A. N.A. N.A. 33.3 26.6
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 13.3 N.A. 73.3 73.3 N.A. N.A. N.A. 73.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 28 % A
% Cys: 0 0 91 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 37 0 0 0 0 37 % E
% Phe: 10 0 0 0 0 0 0 0 0 10 0 0 0 73 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 19 0 10 % G
% His: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 55 0 0 0 % I
% Lys: 55 46 0 0 0 10 0 0 0 28 0 0 0 0 19 % K
% Leu: 0 0 0 55 0 0 10 0 0 0 0 19 0 10 0 % L
% Met: 19 37 0 37 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 73 0 0 0 0 0 91 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 19 0 0 91 10 0 0 0 0 0 % Q
% Arg: 0 19 0 0 10 37 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 28 10 0 0 10 73 0 0 % S
% Thr: 10 0 10 10 0 10 73 64 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 19 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _