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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASAH1 All Species: 29.39
Human Site: T295 Identified Species: 64.67
UniProt: Q13510 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13510 NP_001120977.1 395 44660 T295 S G E G C V I T R D R K E S L
Chimpanzee Pan troglodytes A5A6P2 395 44678 T295 S G E G C V I T R D R K E S L
Rhesus Macaque Macaca mulatta XP_001098342 395 44787 T295 S G E G C V I T R D R K E S L
Dog Lupus familis XP_540012 386 44148 T286 S G E G C V I T R D R K Q S L
Cat Felis silvestris
Mouse Mus musculus Q9WV54 394 44651 T294 S G E G C V I T R E R K E S L
Rat Rattus norvegicus Q6P7S1 394 44425 T294 S G E G C V I T R E R K E S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521781 260 29621 K164 V I N Q R T A K A T V D V Y R
Chicken Gallus gallus
Frog Xenopus laevis NP_001087503 395 44309 T295 S E E G C V I T R S R A V C L
Zebra Danio Brachydanio rerio NP_956871 395 44662 T295 S G E A C I I T R S R T Q N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45686 393 44805 A293 K D E G C I I A R S L D K T A
Sea Urchin Strong. purpuratus XP_784832 392 43432 R292 G Q G A I I T R S I G T K A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 93.9 79.7 N.A. 79.2 82.5 N.A. 49.8 N.A. 61.7 59.7 N.A. N.A. N.A. 38.7 46.3
Protein Similarity: 100 99.2 97.7 89.1 N.A. 91.6 91.6 N.A. 58.7 N.A. 79.4 80.5 N.A. N.A. N.A. 62 65.5
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 0 N.A. 66.6 53.3 N.A. N.A. N.A. 33.3 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 N.A. 66.6 80 N.A. N.A. N.A. 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 10 10 10 0 0 10 0 10 10 % A
% Cys: 0 0 0 0 82 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 37 0 19 0 0 10 % D
% Glu: 0 10 82 0 0 0 0 0 0 19 0 0 46 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 64 10 73 0 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 28 82 0 0 10 0 0 0 0 10 % I
% Lys: 10 0 0 0 0 0 0 10 0 0 0 55 19 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 64 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 10 0 0 0 0 0 0 0 0 19 0 0 % Q
% Arg: 0 0 0 0 10 0 0 10 82 0 73 0 0 0 10 % R
% Ser: 73 0 0 0 0 0 0 0 10 28 0 0 0 55 0 % S
% Thr: 0 0 0 0 0 10 10 73 0 10 0 19 0 10 0 % T
% Val: 10 0 0 0 0 64 0 0 0 0 10 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _