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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASAH1
All Species:
29.09
Human Site:
T377
Identified Species:
64
UniProt:
Q13510
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13510
NP_001120977.1
395
44660
T377
Y
T
T
L
I
D
V
T
K
G
Q
F
E
T
Y
Chimpanzee
Pan troglodytes
A5A6P2
395
44678
T377
Y
T
T
L
I
D
V
T
K
G
Q
F
E
T
Y
Rhesus Macaque
Macaca mulatta
XP_001098342
395
44787
T377
F
T
T
L
I
D
V
T
K
D
Q
F
E
T
Y
Dog
Lupus familis
XP_540012
386
44148
T368
F
T
T
L
M
D
V
T
K
G
Q
Y
E
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV54
394
44651
T376
F
T
T
L
M
D
V
T
K
G
Q
F
E
S
H
Rat
Rattus norvegicus
Q6P7S1
394
44425
T376
F
T
T
L
I
D
V
T
K
D
Q
F
E
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521781
260
29621
F246
M
D
L
S
R
G
K
F
E
T
Y
L
R
D
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087503
395
44309
S377
Y
T
T
L
M
S
V
S
D
N
K
L
E
A
Y
Zebra Danio
Brachydanio rerio
NP_956871
395
44662
S377
Y
T
T
L
M
E
V
S
K
G
T
L
E
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45686
393
44805
E375
Y
T
V
L
M
S
V
E
T
S
R
F
E
T
I
Sea Urchin
Strong. purpuratus
XP_784832
392
43432
R374
Y
T
A
L
M
H
V
R
S
G
T
L
D
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
93.9
79.7
N.A.
79.2
82.5
N.A.
49.8
N.A.
61.7
59.7
N.A.
N.A.
N.A.
38.7
46.3
Protein Similarity:
100
99.2
97.7
89.1
N.A.
91.6
91.6
N.A.
58.7
N.A.
79.4
80.5
N.A.
N.A.
N.A.
62
65.5
P-Site Identity:
100
100
86.6
80
N.A.
73.3
73.3
N.A.
0
N.A.
46.6
53.3
N.A.
N.A.
N.A.
46.6
46.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
93.3
N.A.
6.6
N.A.
66.6
86.6
N.A.
N.A.
N.A.
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
0
55
0
0
10
19
0
0
10
10
0
% D
% Glu:
0
0
0
0
0
10
0
10
10
0
0
0
82
0
0
% E
% Phe:
37
0
0
0
0
0
0
10
0
0
0
55
0
0
10
% F
% Gly:
0
0
0
0
0
10
0
0
0
55
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
19
% H
% Ile:
0
0
0
0
37
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
10
0
64
0
10
0
0
0
0
% K
% Leu:
0
0
10
91
0
0
0
0
0
0
0
37
0
0
0
% L
% Met:
10
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
55
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
10
0
10
0
0
% R
% Ser:
0
0
0
10
0
19
0
19
10
10
0
0
0
28
0
% S
% Thr:
0
91
73
0
0
0
0
55
10
10
19
0
0
55
0
% T
% Val:
0
0
10
0
0
0
91
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
55
0
0
0
0
0
0
0
0
0
10
10
0
0
55
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _