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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AQP6 All Species: 15.45
Human Site: S171 Identified Species: 30.91
UniProt: Q13520 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13520 NP_001643.2 282 29370 S171 D S R Q T S G S P A T M I G I
Chimpanzee Pan troglodytes XP_001157230 282 29322 S171 D S R Q T S G S P A T M I G I
Rhesus Macaque Macaca mulatta XP_001110572 271 28897 S163 N P G T P A L S I G F S V A L
Dog Lupus familis XP_850452 271 28631 I163 S G S P A T M I G I S L S L G
Cat Felis silvestris
Mouse Mus musculus Q8C4A0 293 30690 S168 D G R Q T L A S P A A M I G T
Rat Rattus norvegicus Q9WTY0 276 28841 S168 D S R Q T L G S P A A M I G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518393 255 27145 S147 T L G S P A L S I G F S V V L
Chicken Gallus gallus P28238 262 27053 D154 A S F D D R H D G R P G S A A
Frog Xenopus laevis NP_001079331 273 29418 S163 N V G S P A L S I G L S V T V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V5Z7 245 25557 A136 F D P S L N C A Q A V L I E A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q84RL6 248 25114 E140 V S G I S E I E G V V M E I V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZVX8 278 29482 I166 G T A L G A E I I G T F V L V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 54.6 76.5 N.A. 71.6 76.9 N.A. 50.3 46 51.7 N.A. N.A. 36.1 N.A. N.A. N.A.
Protein Similarity: 100 98.9 66.6 85.1 N.A. 78.5 84 N.A. 59.9 59.9 67 N.A. N.A. 49.6 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 0 N.A. 66.6 80 N.A. 6.6 6.6 6.6 N.A. N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 20 N.A. 66.6 80 N.A. 26.6 6.6 33.3 N.A. N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 32.2 N.A. 37.9 N.A. N.A.
Protein Similarity: N.A. 47.8 N.A. 52.1 N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 9 34 9 9 0 42 17 0 0 17 17 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 34 9 0 9 9 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 9 9 0 0 0 0 9 9 0 % E
% Phe: 9 0 9 0 0 0 0 0 0 0 17 9 0 0 0 % F
% Gly: 9 17 34 0 9 0 25 0 25 34 0 9 0 34 9 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 9 17 34 9 0 0 42 9 17 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 9 9 17 25 0 0 0 9 17 0 17 17 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 42 0 0 0 % M
% Asn: 17 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 9 9 25 0 0 0 34 0 9 0 0 0 0 % P
% Gln: 0 0 0 34 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 34 0 0 9 0 0 0 9 0 0 0 0 0 % R
% Ser: 9 42 9 25 9 17 0 59 0 0 9 25 17 0 0 % S
% Thr: 9 9 0 9 34 9 0 0 0 0 25 0 0 9 17 % T
% Val: 9 9 0 0 0 0 0 0 0 9 17 0 34 9 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _