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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQP6
All Species:
9.39
Human Site:
S274
Identified Species:
18.79
UniProt:
Q13520
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13520
NP_001643.2
282
29370
S274
K
K
E
S
Q
P
G
S
G
A
V
E
M
E
S
Chimpanzee
Pan troglodytes
XP_001157230
282
29322
S274
K
K
E
S
Q
L
G
S
G
A
V
E
M
E
S
Rhesus Macaque
Macaca mulatta
XP_001110572
271
28897
S264
V
E
L
H
S
P
Q
S
L
P
R
G
T
K
A
Dog
Lupus familis
XP_850452
271
28631
M264
P
S
S
G
D
T
E
M
E
N
V
C
Q
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4A0
293
30690
D271
E
S
Q
T
N
S
E
D
T
E
C
L
T
S
P
Rat
Rattus norvegicus
Q9WTY0
276
28841
S269
K
K
E
S
Q
T
N
S
E
D
T
E
V
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518393
255
27145
T248
V
E
L
H
S
P
Q
T
L
P
R
G
N
K
V
Chicken
Gallus gallus
P28238
262
27053
L255
P
E
P
P
A
E
P
L
E
L
K
T
Q
G
L
Frog
Xenopus laevis
NP_001079331
273
29418
L266
E
L
Y
S
A
H
P
L
P
K
V
I
D
K
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Z7
245
25557
D238
F
K
V
R
K
G
D
D
E
T
D
S
Y
D
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q84RL6
248
25114
P241
V
F
I
A
S
Y
Q
P
V
G
Q
Q
E
Y
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVX8
278
29482
A268
L
R
A
A
A
I
K
A
L
A
S
F
R
S
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
54.6
76.5
N.A.
71.6
76.9
N.A.
50.3
46
51.7
N.A.
N.A.
36.1
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
66.6
85.1
N.A.
78.5
84
N.A.
59.9
59.9
67
N.A.
N.A.
49.6
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
13.3
6.6
N.A.
0
46.6
N.A.
6.6
0
13.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
33.3
13.3
N.A.
20
53.3
N.A.
26.6
6.6
26.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
32.2
N.A.
37.9
N.A.
N.A.
Protein Similarity:
N.A.
47.8
N.A.
52.1
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
25
0
0
9
0
25
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% C
% Asp:
0
0
0
0
9
0
9
17
0
9
9
0
9
9
0
% D
% Glu:
17
25
25
0
0
9
17
0
34
9
0
25
9
17
0
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
0
9
0
0
17
% F
% Gly:
0
0
0
9
0
9
17
0
17
9
0
17
0
9
0
% G
% His:
0
0
0
17
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
0
9
0
0
0
% I
% Lys:
25
34
0
0
9
0
9
0
0
9
9
0
0
25
0
% K
% Leu:
9
9
17
0
0
9
0
17
25
9
0
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
17
9
0
% M
% Asn:
0
0
0
0
9
0
9
0
0
9
0
0
9
0
9
% N
% Pro:
17
0
9
9
0
25
17
9
9
17
0
0
0
0
17
% P
% Gln:
0
0
9
0
25
0
25
0
0
0
9
9
17
0
0
% Q
% Arg:
0
9
0
9
0
0
0
0
0
0
17
0
9
0
0
% R
% Ser:
0
17
9
34
25
9
0
34
0
0
9
9
0
25
17
% S
% Thr:
0
0
0
9
0
17
0
9
9
9
9
9
17
0
0
% T
% Val:
25
0
9
0
0
0
0
0
9
0
34
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
9
0
0
0
0
0
0
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _