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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R1A
All Species:
17.75
Human Site:
S165
Identified Species:
43.39
UniProt:
Q13522
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13522
NP_006732.3
171
18939
S165
T
H
I
P
P
L
D
S
K
G
A
N
S
V
_
Chimpanzee
Pan troglodytes
XP_001156163
174
19275
S168
T
H
I
P
P
L
D
S
K
G
A
N
S
V
_
Rhesus Macaque
Macaca mulatta
XP_001110247
171
18891
S165
T
H
I
P
P
L
D
S
K
G
A
N
S
V
_
Dog
Lupus familis
XP_850516
205
22996
P195
L
N
E
P
G
E
G
P
Q
R
P
T
H
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERT9
171
18699
S165
A
H
M
L
P
L
D
S
Q
G
A
S
L
V
_
Rat
Rattus norvegicus
P19103
171
18719
S165
A
H
M
L
P
L
D
S
Q
G
A
S
L
V
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510145
187
19859
R180
P
Q
L
G
S
D
G
R
A
G
K
G
R
M
G
Chicken
Gallus gallus
XP_421970
109
12415
R103
E
E
E
G
I
G
E
R
E
E
E
W
D
H
_
Frog
Xenopus laevis
NP_001082695
185
20793
S157
R
H
S
S
K
E
D
S
L
D
S
H
V
S
D
Zebra Danio
Brachydanio rerio
NP_001002538
171
18448
N162
S
S
G
S
E
Q
K
N
L
S
S
P
S
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85
97
28.7
N.A.
78.9
80.1
N.A.
32
32.7
47.5
35.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89
97.6
42.4
N.A.
84.8
85.9
N.A.
41.7
45
60.5
51.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
57.1
57.1
N.A.
6.6
0
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
78.5
78.5
N.A.
26.6
14.2
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
0
0
10
0
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
60
0
0
10
0
0
10
0
10
% D
% Glu:
10
10
20
0
10
20
10
0
10
10
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
20
10
10
20
0
0
60
0
10
0
0
10
% G
% His:
0
60
0
0
0
0
0
0
0
0
0
10
10
10
0
% H
% Ile:
0
0
30
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
10
0
30
0
10
0
0
0
0
% K
% Leu:
10
0
10
20
0
50
0
0
20
0
0
0
20
0
0
% L
% Met:
0
0
20
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
30
0
0
0
% N
% Pro:
10
0
0
40
50
0
0
10
0
0
10
10
0
10
0
% P
% Gln:
0
10
0
0
0
10
0
0
30
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
20
0
10
0
0
10
0
0
% R
% Ser:
10
10
10
20
10
0
0
60
0
10
20
20
40
20
0
% S
% Thr:
30
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
50
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% _