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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP1R1A All Species: 27.88
Human Site: S46 Identified Species: 68.15
UniProt: Q13522 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13522 NP_006732.3 171 18939 S46 L V L T S D Q S S P E I D E D
Chimpanzee Pan troglodytes XP_001156163 174 19275 S49 L V L T S D Q S S P E I D E D
Rhesus Macaque Macaca mulatta XP_001110247 171 18891 S46 L V L T S D Q S S P E I D E D
Dog Lupus familis XP_850516 205 22996 S45 L F R L S E H S S P E E E A S
Cat Felis silvestris
Mouse Mus musculus Q9ERT9 171 18699 S46 L V L T S D Q S S P E I D E D
Rat Rattus norvegicus P19103 171 18719 S46 L V L T S D Q S S P E V D E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510145 187 19859 V65 C N E R E G R V G V R E K L R
Chicken Gallus gallus XP_421970 109 12415
Frog Xenopus laevis NP_001082695 185 20793 S45 L V L S S D Q S S P E I D E E
Zebra Danio Brachydanio rerio NP_001002538 171 18448 S45 L V I Y N E P S A S G D D K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 97 28.7 N.A. 78.9 80.1 N.A. 32 32.7 47.5 35.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 89 97.6 42.4 N.A. 84.8 85.9 N.A. 41.7 45 60.5 51.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 40 N.A. 100 93.3 N.A. 0 0 86.6 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 53.3 N.A. 100 100 N.A. 6.6 0 100 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 60 0 0 0 0 0 10 70 0 50 % D
% Glu: 0 0 10 0 10 20 0 0 0 0 70 20 10 60 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 10 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 50 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % K
% Leu: 80 0 60 10 0 0 0 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 70 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 60 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 10 10 0 0 10 0 0 0 10 0 0 0 10 % R
% Ser: 0 0 0 10 70 0 0 80 70 10 0 0 0 0 10 % S
% Thr: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 70 0 0 0 0 0 10 0 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _