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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF4B
All Species:
31.82
Human Site:
Y554
Identified Species:
58.33
UniProt:
Q13523
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13523
NP_003904.3
1007
116973
Y554
A
I
V
Q
K
Y
K
Y
L
A
E
D
S
N
M
Chimpanzee
Pan troglodytes
XP_518214
1087
126250
Y634
A
I
V
Q
K
Y
K
Y
L
A
E
D
S
N
M
Rhesus Macaque
Macaca mulatta
XP_001094163
1007
116833
Y554
A
I
V
Q
K
Y
K
Y
L
A
E
D
S
N
M
Dog
Lupus familis
XP_848551
1042
120804
Y589
A
I
V
Q
K
Y
K
Y
L
A
E
D
S
N
M
Cat
Felis silvestris
Mouse
Mus musculus
Q61136
1007
116929
Y554
A
I
V
Q
K
Y
K
Y
L
A
E
D
S
N
I
Rat
Rattus norvegicus
Q5RKH1
1007
116988
Y554
A
I
V
Q
K
Y
K
Y
L
A
E
D
S
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508424
1011
117270
Y558
A
I
V
Q
K
Y
K
Y
L
A
E
D
S
N
L
Chicken
Gallus gallus
XP_001232309
1005
116507
G552
A
I
V
Q
K
Y
K
G
Q
T
E
D
S
N
I
Frog
Xenopus laevis
NP_001088314
991
115012
Y538
A
I
V
Q
K
Y
R
Y
L
N
E
D
S
N
T
Zebra Danio
Brachydanio rerio
NP_998614
1010
116034
G558
I
V
Q
K
Y
K
A
G
N
E
D
S
N
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612010
907
104024
T524
D
N
S
T
S
Q
K
T
C
S
A
K
E
K
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492008
775
90931
D430
G
H
S
G
A
V
H
D
T
L
K
D
N
W
D
Sea Urchin
Strong. purpuratus
XP_791787
924
105587
V508
Q
L
M
Q
K
Y
K
V
A
P
A
E
S
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
99
95.3
N.A.
95.1
95.4
N.A.
93
89.7
80.6
68.8
N.A.
41.4
N.A.
36.8
48.3
Protein Similarity:
100
92.6
99.3
96.1
N.A.
97.5
97.8
N.A.
96.5
94
89.4
78.4
N.A.
57.4
N.A.
51.9
59.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
73.3
80
0
N.A.
6.6
N.A.
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
80
86.6
26.6
N.A.
13.3
N.A.
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
0
8
0
8
0
8
54
16
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
8
77
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
70
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
16
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
70
0
0
0
0
0
0
0
0
0
0
0
0
24
% I
% Lys:
0
0
0
8
77
8
77
0
0
0
8
8
0
8
0
% K
% Leu:
0
8
0
0
0
0
0
0
62
8
0
0
0
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
31
% M
% Asn:
0
8
0
0
0
0
0
0
8
8
0
0
16
70
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
0
8
77
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
16
0
8
0
0
0
0
8
0
8
77
0
0
% S
% Thr:
0
0
0
8
0
0
0
8
8
8
0
0
0
0
16
% T
% Val:
0
8
70
0
0
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
8
77
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _