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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN1
All Species:
14.55
Human Site:
S19
Identified Species:
22.86
UniProt:
Q13526
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13526
NP_006212.1
163
18243
S19
E
K
R
M
S
R
S
S
G
R
V
Y
Y
F
N
Chimpanzee
Pan troglodytes
XP_001161914
174
19574
S19
E
K
R
M
S
R
S
S
G
R
V
Y
Y
F
N
Rhesus Macaque
Macaca mulatta
XP_001099116
145
16071
Dog
Lupus familis
XP_542080
163
18285
S19
E
K
R
M
S
R
S
S
G
R
V
Y
Y
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR7
165
18352
R21
R
M
S
R
S
S
G
R
V
Y
Y
F
N
H
I
Rat
Rattus norvegicus
NP_001100171
165
18314
R21
R
M
S
R
S
S
G
R
V
Y
Y
F
N
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089028
159
17622
M15
P
P
G
W
E
K
R
M
S
R
S
S
G
R
V
Zebra Danio
Brachydanio rerio
NP_957042
159
17688
M15
P
S
G
W
E
K
R
M
S
R
S
S
G
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54353
166
18358
S22
T
S
R
S
T
G
M
S
Y
Y
L
N
M
Y
T
Honey Bee
Apis mellifera
XP_624205
162
18033
T18
E
K
R
L
S
R
S
T
G
Q
H
Y
Y
L
N
Nematode Worm
Caenorhab. elegans
NP_494393
168
19158
F24
S
N
D
R
V
Y
Y
F
N
T
A
T
G
R
S
Sea Urchin
Strong. purpuratus
XP_788025
152
17114
W9
A
D
D
L
P
E
G
W
E
I
R
Y
S
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL42
119
12996
Baker's Yeast
Sacchar. cerevisiae
P22696
170
19386
E26
Y
S
K
S
K
K
R
E
Y
F
F
N
P
E
T
Red Bread Mold
Neurospora crassa
O60045
182
20596
P38
T
K
T
S
R
W
E
P
P
S
G
T
D
V
D
Conservation
Percent
Protein Identity:
100
93.6
81.5
98.7
N.A.
95.1
95.7
N.A.
N.A.
N.A.
86.5
79.1
N.A.
56
65
57.1
55.2
Protein Similarity:
100
93.6
84
98.7
N.A.
96.9
96.9
N.A.
N.A.
N.A.
93.8
88.9
N.A.
65
74.8
67.2
70.5
P-Site Identity:
100
100
0
100
N.A.
6.6
6.6
N.A.
N.A.
N.A.
6.6
6.6
N.A.
13.3
66.6
0
6.6
P-Site Similarity:
100
100
0
100
N.A.
13.3
13.3
N.A.
N.A.
N.A.
13.3
13.3
N.A.
33.3
86.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
44.1
50.5
Protein Similarity:
N.A.
N.A.
N.A.
53.9
60.5
63.7
P-Site Identity:
N.A.
N.A.
N.A.
0
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
14
0
0
0
0
0
0
0
0
0
7
0
7
% D
% Glu:
27
0
0
0
14
7
7
7
7
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
7
7
14
0
20
0
% F
% Gly:
0
0
14
0
0
7
20
0
27
0
7
0
20
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
14
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
14
% I
% Lys:
0
34
7
0
7
20
0
0
0
0
0
0
0
7
0
% K
% Leu:
0
0
0
14
0
0
0
0
0
0
7
0
0
7
0
% L
% Met:
0
14
0
20
0
0
7
14
0
0
0
0
7
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
7
0
0
14
14
0
27
% N
% Pro:
14
7
0
0
7
0
0
7
7
0
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
14
0
34
20
7
27
20
14
0
34
7
0
0
20
0
% R
% Ser:
7
20
14
20
40
14
27
27
14
7
14
14
7
0
7
% S
% Thr:
14
0
7
0
7
0
0
7
0
7
0
14
0
0
20
% T
% Val:
0
0
0
0
7
0
0
0
14
0
20
0
0
7
14
% V
% Trp:
0
0
0
14
0
7
0
7
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
7
7
0
14
20
14
34
27
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _