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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN1
All Species:
29.09
Human Site:
S65
Identified Species:
45.71
UniProt:
Q13526
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13526
NP_006212.1
163
18243
S65
S
H
L
L
V
K
H
S
Q
S
R
R
P
S
S
Chimpanzee
Pan troglodytes
XP_001161914
174
19574
S65
S
H
L
L
V
K
H
S
Q
S
R
R
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001099116
145
16071
G48
S
S
S
G
G
K
N
G
Q
G
E
P
A
R
V
Dog
Lupus familis
XP_542080
163
18285
S65
S
H
L
L
V
K
H
S
Q
S
R
R
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR7
165
18352
S67
S
H
L
L
V
K
H
S
Q
S
R
R
P
S
S
Rat
Rattus norvegicus
NP_001100171
165
18314
S67
S
H
L
L
V
K
H
S
Q
S
R
R
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089028
159
17622
N61
S
H
L
L
V
K
H
N
Q
S
R
R
P
S
S
Zebra Danio
Brachydanio rerio
NP_957042
159
17688
S61
S
H
L
L
V
K
H
S
Q
S
R
R
P
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54353
166
18358
K68
L
H
L
L
V
K
H
K
G
S
R
R
P
S
S
Honey Bee
Apis mellifera
XP_624205
162
18033
S64
S
H
L
L
V
K
H
S
G
S
R
R
P
S
S
Nematode Worm
Caenorhab. elegans
NP_494393
168
19158
S70
R
N
P
S
S
W
R
S
D
H
I
T
R
S
K
Sea Urchin
Strong. purpuratus
XP_788025
152
17114
D55
H
L
L
V
K
H
R
D
S
R
R
P
A
S
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL42
119
12996
R21
I
K
H
Q
G
S
R
R
K
A
S
W
K
D
P
Baker's Yeast
Sacchar. cerevisiae
P22696
170
19386
S72
I
L
I
K
H
K
D
S
R
R
P
A
S
H
R
Red Bread Mold
Neurospora crassa
O60045
182
20596
N84
A
H
L
L
V
K
H
N
Q
S
R
R
P
S
S
Conservation
Percent
Protein Identity:
100
93.6
81.5
98.7
N.A.
95.1
95.7
N.A.
N.A.
N.A.
86.5
79.1
N.A.
56
65
57.1
55.2
Protein Similarity:
100
93.6
84
98.7
N.A.
96.9
96.9
N.A.
N.A.
N.A.
93.8
88.9
N.A.
65
74.8
67.2
70.5
P-Site Identity:
100
100
20
100
N.A.
100
100
N.A.
N.A.
N.A.
93.3
100
N.A.
80
93.3
13.3
20
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
N.A.
N.A.
100
100
N.A.
80
93.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
44.1
50.5
Protein Similarity:
N.A.
N.A.
N.A.
53.9
60.5
63.7
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
86.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
7
0
7
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
7
7
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
14
0
0
7
14
7
0
0
0
0
0
% G
% His:
7
67
7
0
7
7
67
0
0
7
0
0
0
7
0
% H
% Ile:
14
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
7
0
7
7
80
0
7
7
0
0
0
7
0
7
% K
% Leu:
7
14
74
67
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
7
14
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
7
14
67
0
7
% P
% Gln:
0
0
0
7
0
0
0
0
60
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
20
7
7
14
74
67
7
7
7
% R
% Ser:
60
7
7
7
7
7
0
60
7
67
7
0
7
80
67
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
7
67
0
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _