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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATR All Species: 29.7
Human Site: S1288 Identified Species: 59.39
UniProt: Q13535 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13535 NP_001175.2 2644 301367 S1288 L Q T T L Q L S M K A I Q H E
Chimpanzee Pan troglodytes XP_516792 2646 301618 S1290 L Q T T L Q L S M K A I Q H E
Rhesus Macaque Macaca mulatta XP_001112149 2644 301431 S1288 L Q T T L Q L S M K A I Q H E
Dog Lupus familis XP_534295 2644 301635 S1291 L Q T T L Q L S M K A I Q H E
Cat Felis silvestris
Mouse Mus musculus Q9JKK8 2635 300205 S1288 L Q T T L Q L S M K A I Q H E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q9DE14 2654 301441 S1303 L Q T A M Q L S I R A I Q H E
Zebra Danio Brachydanio rerio XP_696163 2643 299171 S1291 M Q A A L Q L S M R A I Q H E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXG8 2517 289311 P1219 A I D A S Y L P S N Y N F A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786094 2665 299705 S1304 L R T L L K R S L K G V S H E
Poplar Tree Populus trichocarpa XP_002305538 2740 307311 V1301 L K D Q L R D V V D G L N H E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FKS4 2702 302347 I1260 L K D Q L R D I V N G M K H E
Baker's Yeast Sacchar. cerevisiae P38111 2368 273324 D1090 K K V G Q T S D I T L V L G A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.7 94.9 N.A. 90.4 N.A. N.A. N.A. N.A. 72.8 65.3 N.A. 26.1 N.A. N.A. 43
Protein Similarity: 100 99.1 99.5 97.2 N.A. 95.1 N.A. N.A. N.A. N.A. 83.5 78.5 N.A. 47.6 N.A. N.A. 60.8
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. 73.3 73.3 N.A. 6.6 N.A. N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. 93.3 86.6 N.A. 6.6 N.A. N.A. 73.3
Percent
Protein Identity: 27 N.A. N.A. 26.5 21.9 N.A.
Protein Similarity: 46 N.A. N.A. 46.1 41.7 N.A.
P-Site Identity: 26.6 N.A. N.A. 26.6 0 N.A.
P-Site Similarity: 53.3 N.A. N.A. 60 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 25 0 0 0 0 0 0 59 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 25 0 0 0 17 9 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 25 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 84 0 % H
% Ile: 0 9 0 0 0 0 0 9 17 0 0 59 0 0 0 % I
% Lys: 9 25 0 0 0 9 0 0 0 50 0 0 9 0 0 % K
% Leu: 75 0 0 9 75 0 67 0 9 0 9 9 9 0 0 % L
% Met: 9 0 0 0 9 0 0 0 50 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 17 0 9 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % P
% Gln: 0 59 0 17 9 59 0 0 0 0 0 0 59 0 0 % Q
% Arg: 0 9 0 0 0 17 9 0 0 17 0 0 0 0 0 % R
% Ser: 0 0 0 0 9 0 9 67 9 0 0 0 9 0 9 % S
% Thr: 0 0 59 42 0 9 0 0 0 9 0 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 9 17 0 0 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _