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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATR All Species: 19.39
Human Site: S428 Identified Species: 38.79
UniProt: Q13535 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13535 NP_001175.2 2644 301367 S428 S S N S D G I S P K R R R L S
Chimpanzee Pan troglodytes XP_516792 2646 301618 S430 S S N S D G I S P K R R R L S
Rhesus Macaque Macaca mulatta XP_001112149 2644 301431 S428 S S N S D G I S P K R R R L S
Dog Lupus familis XP_534295 2644 301635 S431 S S N S D G I S A K R R R L S
Cat Felis silvestris
Mouse Mus musculus Q9JKK8 2635 300205 S431 S G N N D E V S P K R R K L S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q9DE14 2654 301441 S434 E G G G S S S S D E V Q E K R
Zebra Danio Brachydanio rerio XP_696163 2643 299171 E434 A D P R M Y E E E L P A K R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXG8 2517 289311 A415 S Q S Q H K I A E H E G H I D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786094 2665 299705 T452 R S N H G G T T E D I V I D L
Poplar Tree Populus trichocarpa XP_002305538 2740 307311 N426 R V G G R M E N N D D A S L S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FKS4 2702 302347 R431 E D E S T Y K R K R Q K V G D
Baker's Yeast Sacchar. cerevisiae P38111 2368 273324 L302 M A K G I L R L Y S L C I S N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.7 94.9 N.A. 90.4 N.A. N.A. N.A. N.A. 72.8 65.3 N.A. 26.1 N.A. N.A. 43
Protein Similarity: 100 99.1 99.5 97.2 N.A. 95.1 N.A. N.A. N.A. N.A. 83.5 78.5 N.A. 47.6 N.A. N.A. 60.8
P-Site Identity: 100 100 100 93.3 N.A. 66.6 N.A. N.A. N.A. N.A. 6.6 0 N.A. 13.3 N.A. N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 N.A. N.A. N.A. N.A. 20 13.3 N.A. 33.3 N.A. N.A. 26.6
Percent
Protein Identity: 27 N.A. N.A. 26.5 21.9 N.A.
Protein Similarity: 46 N.A. N.A. 46.1 41.7 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 20 N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 0 9 9 0 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 17 0 0 42 0 0 0 9 17 9 0 0 9 17 % D
% Glu: 17 0 9 0 0 9 17 9 25 9 9 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 17 25 9 42 0 0 0 0 0 9 0 9 0 % G
% His: 0 0 0 9 9 0 0 0 0 9 0 0 9 0 0 % H
% Ile: 0 0 0 0 9 0 42 0 0 0 9 0 17 9 0 % I
% Lys: 0 0 9 0 0 9 9 0 9 42 0 9 17 9 0 % K
% Leu: 0 0 0 0 0 9 0 9 0 9 9 0 0 50 9 % L
% Met: 9 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 50 9 0 0 0 9 9 0 0 0 0 0 9 % N
% Pro: 0 0 9 0 0 0 0 0 34 0 9 0 0 0 9 % P
% Gln: 0 9 0 9 0 0 0 0 0 0 9 9 0 0 0 % Q
% Arg: 17 0 0 9 9 0 9 9 0 9 42 42 34 9 9 % R
% Ser: 50 42 9 42 9 9 9 50 0 9 0 0 9 9 50 % S
% Thr: 0 0 0 0 9 0 9 9 0 0 0 0 0 0 0 % T
% Val: 0 9 0 0 0 0 9 0 0 0 9 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 17 0 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _