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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4EBP2
All Species:
13.92
Human Site:
S7
Identified Species:
25.52
UniProt:
Q13542
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13542
NP_004087.1
120
12939
S7
_
M
S
S
S
A
G
S
G
H
Q
P
S
Q
S
Chimpanzee
Pan troglodytes
XP_001136348
133
14823
F20
C
L
Q
V
Q
E
N
F
S
Q
S
R
T
I
P
Rhesus Macaque
Macaca mulatta
XP_001105359
135
14300
S7
_
M
S
S
S
A
G
S
G
H
P
P
S
Q
S
Dog
Lupus familis
XP_546145
120
12947
S7
_
M
S
S
S
A
G
S
G
H
Q
P
S
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
P70445
120
12880
G7
_
M
S
A
S
A
G
G
S
H
Q
P
S
Q
S
Rat
Rattus norvegicus
Q62622
117
12385
C7
_
M
S
A
G
S
S
C
S
Q
T
P
S
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508892
269
29447
K159
F
P
A
A
K
T
A
K
N
G
Q
N
T
Q
C
Chicken
Gallus gallus
XP_424384
116
12481
G8
M
S
G
R
C
C
Q
G
Q
T
P
S
R
D
I
Frog
Xenopus laevis
NP_001084529
113
12411
S8
M
S
A
G
H
Q
H
S
Q
S
R
A
I
P
T
Zebra Danio
Brachydanio rerio
Q98TT6
112
12513
S10
T
N
T
Q
Q
S
K
S
C
P
I
P
T
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477295
117
12857
A7
_
M
S
A
S
P
T
A
R
Q
A
I
T
Q
A
Honey Bee
Apis mellifera
XP_001120078
115
12648
S13
I
A
R
Q
A
T
Q
S
Q
N
I
P
S
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001077103
113
12005
D15
R
Q
L
S
A
G
R
D
I
P
S
K
R
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
66.6
99.1
N.A.
95
57.5
N.A.
35.3
55.8
76.6
57.5
N.A.
39.1
45.8
N.A.
55
Protein Similarity:
100
77.4
72.5
99.1
N.A.
96.6
73.3
N.A.
37.9
72.5
85
69.1
N.A.
59.1
65.8
N.A.
66.6
P-Site Identity:
100
0
92.8
100
N.A.
78.5
28.5
N.A.
13.3
0
6.6
13.3
N.A.
28.5
20
N.A.
6.6
P-Site Similarity:
100
13.3
92.8
100
N.A.
85.7
57.1
N.A.
33.3
0
26.6
40
N.A.
57.1
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
31
16
31
8
8
0
0
8
8
0
0
16
% A
% Cys:
8
0
0
0
8
8
0
8
8
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
8
31
16
24
8
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
8
0
0
31
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
16
8
8
8
8
% I
% Lys:
0
0
0
0
8
0
8
8
0
0
0
8
0
8
0
% K
% Leu:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
16
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
8
8
0
8
0
0
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
16
16
54
0
8
8
% P
% Gln:
0
8
8
16
16
8
16
0
24
24
31
0
0
47
0
% Q
% Arg:
8
0
8
8
0
0
8
0
8
0
8
8
16
16
8
% R
% Ser:
0
16
47
31
39
16
8
47
24
8
16
8
47
0
31
% S
% Thr:
8
0
8
0
0
16
8
0
0
8
8
0
31
0
16
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _