KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4EBP2
All Species:
28.48
Human Site:
T46
Identified Species:
52.22
UniProt:
Q13542
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13542
NP_004087.1
120
12939
T46
G
G
T
L
F
S
T
T
P
G
G
T
R
I
I
Chimpanzee
Pan troglodytes
XP_001136348
133
14823
T59
G
G
A
L
F
S
T
T
R
G
G
T
Q
I
F
Rhesus Macaque
Macaca mulatta
XP_001105359
135
14300
T46
E
G
T
L
F
S
T
T
P
G
G
T
R
I
I
Dog
Lupus familis
XP_546145
120
12947
T46
G
G
T
L
F
S
T
T
P
G
G
T
R
I
I
Cat
Felis silvestris
Mouse
Mus musculus
P70445
120
12880
T46
G
G
T
L
F
S
T
T
P
G
G
T
R
I
I
Rat
Rattus norvegicus
Q62622
117
12385
P46
G
T
L
F
S
T
T
P
G
G
T
R
I
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508892
269
29447
T198
V
S
G
Q
G
T
G
T
P
G
G
T
R
I
I
Chicken
Gallus gallus
XP_424384
116
12481
T47
G
G
T
V
F
G
T
T
P
G
G
T
R
I
I
Frog
Xenopus laevis
NP_001084529
113
12411
R47
S
T
T
P
G
G
T
R
I
I
Y
D
R
K
F
Zebra Danio
Brachydanio rerio
Q98TT6
112
12513
I49
T
P
G
G
T
R
I
I
Y
D
R
K
F
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477295
117
12857
T46
G
G
T
L
Y
S
T
T
P
G
G
T
K
L
I
Honey Bee
Apis mellifera
XP_001120078
115
12648
V52
T
P
G
G
T
R
I
V
Y
E
R
D
F
L
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001077103
113
12005
D54
G
G
T
R
I
I
Y
D
R
N
F
L
L
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
66.6
99.1
N.A.
95
57.5
N.A.
35.3
55.8
76.6
57.5
N.A.
39.1
45.8
N.A.
55
Protein Similarity:
100
77.4
72.5
99.1
N.A.
96.6
73.3
N.A.
37.9
72.5
85
69.1
N.A.
59.1
65.8
N.A.
66.6
P-Site Identity:
100
73.3
93.3
100
N.A.
100
26.6
N.A.
53.3
86.6
20
0
N.A.
80
0
N.A.
20
P-Site Similarity:
100
80
93.3
100
N.A.
100
33.3
N.A.
60
93.3
20
13.3
N.A.
100
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
8
0
16
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
8
47
0
0
0
0
0
8
0
16
0
16
% F
% Gly:
62
62
24
16
16
16
8
0
8
70
62
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
16
8
8
8
0
0
8
62
54
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% K
% Leu:
0
0
8
47
0
0
0
0
0
0
0
8
8
24
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
16
0
8
0
0
0
8
54
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
16
0
8
16
0
16
8
54
0
0
% R
% Ser:
8
8
0
0
8
47
0
0
0
0
0
0
0
0
0
% S
% Thr:
16
16
62
0
16
16
70
62
0
0
8
62
0
0
0
% T
% Val:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
16
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _