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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4EBP2
All Species:
30
Human Site:
T50
Identified Species:
55
UniProt:
Q13542
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13542
NP_004087.1
120
12939
T50
F
S
T
T
P
G
G
T
R
I
I
Y
D
R
K
Chimpanzee
Pan troglodytes
XP_001136348
133
14823
T63
F
S
T
T
R
G
G
T
Q
I
F
Y
D
R
K
Rhesus Macaque
Macaca mulatta
XP_001105359
135
14300
T50
F
S
T
T
P
G
G
T
R
I
I
Y
D
K
K
Dog
Lupus familis
XP_546145
120
12947
T50
F
S
T
T
P
G
G
T
R
I
I
Y
D
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P70445
120
12880
T50
F
S
T
T
P
G
G
T
R
I
I
Y
D
R
K
Rat
Rattus norvegicus
Q62622
117
12385
R50
S
T
T
P
G
G
T
R
I
I
Y
D
R
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508892
269
29447
T202
G
T
G
T
P
G
G
T
R
I
I
Y
D
R
K
Chicken
Gallus gallus
XP_424384
116
12481
T51
F
G
T
T
P
G
G
T
R
I
I
Y
D
R
K
Frog
Xenopus laevis
NP_001084529
113
12411
D51
G
G
T
R
I
I
Y
D
R
K
F
L
L
D
R
Zebra Danio
Brachydanio rerio
Q98TT6
112
12513
K53
T
R
I
I
Y
D
R
K
F
L
L
D
C
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477295
117
12857
T50
Y
S
T
T
P
G
G
T
K
L
I
Y
E
R
A
Honey Bee
Apis mellifera
XP_001120078
115
12648
D56
T
R
I
V
Y
E
R
D
F
L
M
N
L
R
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001077103
113
12005
L58
I
I
Y
D
R
N
F
L
L
N
M
R
N
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
66.6
99.1
N.A.
95
57.5
N.A.
35.3
55.8
76.6
57.5
N.A.
39.1
45.8
N.A.
55
Protein Similarity:
100
77.4
72.5
99.1
N.A.
96.6
73.3
N.A.
37.9
72.5
85
69.1
N.A.
59.1
65.8
N.A.
66.6
P-Site Identity:
100
80
93.3
100
N.A.
100
20
N.A.
80
93.3
13.3
6.6
N.A.
66.6
6.6
N.A.
0
P-Site Similarity:
100
86.6
100
100
N.A.
100
33.3
N.A.
86.6
93.3
20
20
N.A.
93.3
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
8
0
16
0
0
0
16
54
8
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% E
% Phe:
47
0
0
0
0
0
8
0
16
0
16
0
0
0
8
% F
% Gly:
16
16
8
0
8
70
62
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
16
8
8
8
0
0
8
62
54
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
8
0
0
0
16
54
% K
% Leu:
0
0
0
0
0
0
0
8
8
24
8
8
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
8
8
0
16
% N
% Pro:
0
0
0
8
54
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
16
0
8
16
0
16
8
54
0
0
8
8
70
8
% R
% Ser:
8
47
0
0
0
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
16
16
70
62
0
0
8
62
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
16
0
8
0
0
0
8
62
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _