KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4EBP2
All Species:
30.61
Human Site:
T70
Identified Species:
56.11
UniProt:
Q13542
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13542
NP_004087.1
120
12939
T70
R
N
S
P
M
A
Q
T
P
P
C
H
L
P
N
Chimpanzee
Pan troglodytes
XP_001136348
133
14823
T83
C
N
S
P
M
V
Q
T
P
P
C
H
L
P
N
Rhesus Macaque
Macaca mulatta
XP_001105359
135
14300
T70
R
S
S
P
T
A
R
T
P
P
C
H
L
P
N
Dog
Lupus familis
XP_546145
120
12947
T70
R
N
S
P
M
A
Q
T
P
P
C
H
L
P
N
Cat
Felis silvestris
Mouse
Mus musculus
P70445
120
12880
T70
R
N
S
P
M
A
Q
T
P
P
C
H
L
P
N
Rat
Rattus norvegicus
Q62622
117
12385
P70
N
S
P
V
A
K
T
P
P
K
D
L
P
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508892
269
29447
T222
R
S
S
P
M
A
Q
T
P
P
C
H
L
P
N
Chicken
Gallus gallus
XP_424384
116
12481
T71
R
N
S
P
V
A
K
T
P
P
S
D
L
P
D
Frog
Xenopus laevis
NP_001084529
113
12411
L71
A
Q
T
P
P
R
R
L
P
D
I
P
G
V
T
Zebra Danio
Brachydanio rerio
Q98TT6
112
12513
Q73
T
P
P
C
C
L
P
Q
I
P
G
V
T
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477295
117
12857
T70
R
G
S
P
L
S
Q
T
P
P
S
N
V
P
S
Honey Bee
Apis mellifera
XP_001120078
115
12648
S76
T
P
P
R
N
M
P
S
I
P
G
E
L
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001077103
113
12005
P78
P
K
N
L
P
S
I
P
G
V
T
C
P
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
66.6
99.1
N.A.
95
57.5
N.A.
35.3
55.8
76.6
57.5
N.A.
39.1
45.8
N.A.
55
Protein Similarity:
100
77.4
72.5
99.1
N.A.
96.6
73.3
N.A.
37.9
72.5
85
69.1
N.A.
59.1
65.8
N.A.
66.6
P-Site Identity:
100
86.6
80
100
N.A.
100
6.6
N.A.
93.3
66.6
13.3
6.6
N.A.
53.3
13.3
N.A.
0
P-Site Similarity:
100
86.6
93.3
100
N.A.
100
13.3
N.A.
100
86.6
26.6
6.6
N.A.
86.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
47
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
8
8
0
0
0
0
0
47
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
0
16
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
16
0
8
0
0
8
8
% I
% Lys:
0
8
0
0
0
8
8
0
0
8
0
0
0
0
8
% K
% Leu:
0
0
0
8
8
8
0
8
0
0
0
8
62
8
0
% L
% Met:
0
0
0
0
39
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
39
8
0
8
0
0
0
0
0
0
8
0
0
47
% N
% Pro:
8
16
24
70
16
0
16
16
77
77
0
8
16
62
8
% P
% Gln:
0
8
0
0
0
0
47
8
0
0
0
0
0
0
0
% Q
% Arg:
54
0
0
8
0
8
16
0
0
0
0
0
0
0
0
% R
% Ser:
0
24
62
0
0
16
0
8
0
0
16
0
0
0
8
% S
% Thr:
16
0
8
0
8
0
8
62
0
0
8
0
8
8
8
% T
% Val:
0
0
0
8
8
8
0
0
0
8
0
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _