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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4EBP2
All Species:
14.55
Human Site:
T86
Identified Species:
26.67
UniProt:
Q13542
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13542
NP_004087.1
120
12939
T86
P
G
V
T
S
P
G
T
L
I
E
D
S
K
V
Chimpanzee
Pan troglodytes
XP_001136348
133
14823
T99
P
E
V
T
S
P
G
T
L
I
E
D
S
R
V
Rhesus Macaque
Macaca mulatta
XP_001105359
135
14300
T86
P
G
V
T
S
P
G
T
L
S
E
D
S
K
V
Dog
Lupus familis
XP_546145
120
12947
T86
P
G
V
T
S
P
G
T
L
I
E
D
S
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P70445
120
12880
A86
P
G
V
T
S
P
G
A
L
I
E
D
S
K
V
Rat
Rattus norvegicus
Q62622
117
12385
D86
G
V
T
S
P
T
S
D
E
P
P
M
Q
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508892
269
29447
A238
P
G
V
T
S
P
G
A
L
I
D
D
P
K
V
Chicken
Gallus gallus
XP_424384
116
12481
V87
P
G
V
T
S
P
I
V
E
E
L
K
I
E
N
Frog
Xenopus laevis
NP_001084529
113
12411
P87
P
N
T
V
V
E
E
P
K
V
E
T
N
N
L
Zebra Danio
Brachydanio rerio
Q98TT6
112
12513
Q89
L
H
P
V
S
K
L
Q
E
L
K
E
E
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477295
117
12857
T86
L
L
R
G
T
P
R
T
P
F
R
K
C
V
P
Honey Bee
Apis mellifera
XP_001120078
115
12648
S92
A
S
P
N
P
L
T
S
V
K
N
Q
I
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001077103
113
12005
G94
A
G
A
E
K
P
N
G
A
R
K
T
A
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
66.6
99.1
N.A.
95
57.5
N.A.
35.3
55.8
76.6
57.5
N.A.
39.1
45.8
N.A.
55
Protein Similarity:
100
77.4
72.5
99.1
N.A.
96.6
73.3
N.A.
37.9
72.5
85
69.1
N.A.
59.1
65.8
N.A.
66.6
P-Site Identity:
100
86.6
93.3
100
N.A.
93.3
0
N.A.
80
40
13.3
6.6
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
100
N.A.
93.3
6.6
N.A.
86.6
46.6
33.3
26.6
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
0
0
16
8
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
8
47
0
0
0
% D
% Glu:
0
8
0
8
0
8
8
0
24
8
47
8
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
54
0
8
0
0
47
8
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
39
0
0
16
8
0
% I
% Lys:
0
0
0
0
8
8
0
0
8
8
16
16
0
39
16
% K
% Leu:
16
8
0
0
0
8
8
0
47
8
8
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
8
0
0
8
0
0
0
8
0
8
8
8
% N
% Pro:
62
0
16
0
16
70
0
8
8
8
8
0
8
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% Q
% Arg:
0
0
8
0
0
0
8
0
0
8
8
0
0
8
0
% R
% Ser:
0
8
0
8
62
0
8
8
0
8
0
0
39
0
8
% S
% Thr:
0
0
16
54
8
8
8
39
0
0
0
16
0
8
0
% T
% Val:
0
8
54
16
8
0
0
8
8
8
0
0
0
8
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _