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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIPK1
All Species:
9.09
Human Site:
Y510
Identified Species:
22.22
UniProt:
Q13546
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13546
NP_003795.2
671
75931
Y510
I
P
V
P
E
T
N
Y
L
G
N
T
P
T
M
Chimpanzee
Pan troglodytes
XP_001160973
841
93994
Y680
I
P
V
P
E
T
N
Y
L
G
N
T
P
T
M
Rhesus Macaque
Macaca mulatta
XP_001091986
671
76080
Y510
I
P
V
P
E
T
N
Y
L
G
N
T
P
T
M
Dog
Lupus familis
XP_545317
828
93080
N669
K
T
P
V
P
E
T
N
L
L
G
N
T
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60855
656
74836
I499
T
P
V
P
E
T
N
I
P
G
S
T
P
T
M
Rat
Rattus norvegicus
NP_001100820
658
74738
M508
L
P
G
S
I
P
T
M
P
Y
I
S
L
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510675
922
101658
V721
F
G
L
H
K
I
P
V
P
E
T
N
F
D
P
Chicken
Gallus gallus
NP_989733
663
75503
Q509
Q
S
S
A
S
Q
Q
Q
K
N
A
A
D
T
D
Frog
Xenopus laevis
NP_001089189
667
75677
F513
E
Q
Q
T
S
H
Q
F
A
R
D
A
R
T
G
Zebra Danio
Brachydanio rerio
NP_001036815
661
73940
A509
N
S
P
V
T
Y
P
A
S
D
S
A
F
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
94.1
63.8
N.A.
70.1
70.7
N.A.
42.6
49
43.8
39.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.6
96.7
70.4
N.A.
81
80.7
N.A.
53
66
60.5
57.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
73.3
6.6
N.A.
0
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
80
20
N.A.
13.3
6.6
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
10
0
10
30
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
10
0
10
10
10
% D
% Glu:
10
0
0
0
40
10
0
0
0
10
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
0
20
0
0
% F
% Gly:
0
10
10
0
0
0
0
0
0
40
10
0
0
0
10
% G
% His:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
30
0
0
0
10
10
0
10
0
0
10
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
0
0
0
0
40
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
40
% M
% Asn:
10
0
0
0
0
0
40
10
0
10
30
20
0
0
0
% N
% Pro:
0
50
20
40
10
10
20
0
30
0
0
0
40
20
20
% P
% Gln:
10
10
10
0
0
10
20
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
0
20
10
10
20
0
0
0
10
0
20
10
0
0
0
% S
% Thr:
10
10
0
10
10
40
20
0
0
0
10
40
10
60
10
% T
% Val:
0
0
40
20
0
0
0
10
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
30
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _