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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKD2
All Species:
21.21
Human Site:
S219
Identified Species:
58.33
UniProt:
Q13563
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13563
NP_000288.1
968
109691
S219
N
R
E
K
Y
L
K
S
V
L
R
E
L
V
T
Chimpanzee
Pan troglodytes
XP_001168415
805
91946
F137
T
K
V
M
S
E
L
F
L
H
T
P
S
D
T
Rhesus Macaque
Macaca mulatta
XP_001099242
969
109684
S220
N
R
E
K
Y
L
K
S
V
L
R
E
L
V
T
Dog
Lupus familis
XP_544974
908
103725
S159
S
R
E
K
Y
L
K
S
V
L
R
E
M
A
T
Cat
Felis silvestris
Mouse
Mus musculus
O35245
966
108978
S217
N
R
E
K
Y
L
K
S
V
L
R
E
L
V
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509851
916
103775
T147
R
K
E
L
E
I
R
T
T
L
Q
E
L
S
I
Chicken
Gallus gallus
NP_001026311
881
100576
Y140
V
L
R
E
L
I
T
Y
V
I
F
L
V
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1S7
716
80416
G48
K
N
P
A
Q
K
E
G
I
S
F
S
Q
A
L
Sea Urchin
Strong. purpuratus
NP_999827
907
103454
T155
D
K
E
L
H
V
K
T
T
L
R
E
L
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43
98.4
88
N.A.
90.2
N.A.
N.A.
40
74.6
N.A.
N.A.
N.A.
N.A.
N.A.
29.8
48.6
Protein Similarity:
100
60.3
98.9
90.5
N.A.
93.8
N.A.
N.A.
56.4
83.3
N.A.
N.A.
N.A.
N.A.
N.A.
46.2
64.9
P-Site Identity:
100
6.6
100
80
N.A.
100
N.A.
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
40
P-Site Similarity:
100
20
100
93.3
N.A.
100
N.A.
N.A.
60
40
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
0
0
0
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
67
12
12
12
12
0
0
0
0
67
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
23
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
23
0
0
12
12
0
0
0
0
23
% I
% Lys:
12
34
0
45
0
12
56
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
23
12
45
12
0
12
67
0
12
56
0
23
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
34
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
12
0
12
0
0
% Q
% Arg:
12
45
12
0
0
0
12
0
0
0
56
0
0
0
0
% R
% Ser:
12
0
0
0
12
0
0
45
0
12
0
12
12
12
0
% S
% Thr:
12
0
0
0
0
0
12
23
23
0
12
0
0
0
56
% T
% Val:
12
0
12
0
0
12
0
0
56
0
0
0
12
45
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
45
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _