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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF5
All Species:
4.55
Human Site:
T168
Identified Species:
11.11
UniProt:
Q13568
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13568
NP_001092097.1
498
56044
T168
E
D
V
K
W
P
P
T
L
Q
P
P
T
L
R
Chimpanzee
Pan troglodytes
XP_001154220
499
56107
T168
E
D
V
K
W
P
P
T
L
Q
P
P
T
L
R
Rhesus Macaque
Macaca mulatta
XP_001092227
484
54595
M154
E
E
E
E
L
Q
R
M
L
P
S
L
S
L
T
Dog
Lupus familis
XP_539383
569
62668
M235
A
V
Q
P
G
P
P
M
A
P
Y
S
L
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P56477
497
55986
N168
P
A
L
P
G
P
P
N
A
P
Y
S
L
P
K
Rat
Rattus norvegicus
P23570
328
37046
N49
A
L
H
G
W
D
I
N
K
D
A
C
L
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509633
574
64162
M243
G
Q
V
P
V
P
A
M
Q
P
Y
P
W
L
K
Chicken
Gallus gallus
Q90871
425
49152
L146
S
P
S
A
I
D
D
L
M
K
E
P
P
C
V
Frog
Xenopus laevis
NP_001081215
459
52348
I162
E
P
F
N
C
L
N
I
N
D
S
P
I
G
S
Zebra Danio
Brachydanio rerio
NP_956892
492
54858
G166
A
A
V
W
T
P
P
G
S
V
S
P
L
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.5
78.9
N.A.
86.7
23.2
N.A.
70.2
31.9
46.5
49.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
94.7
81.7
N.A.
89.5
37.3
N.A.
74.7
46.7
62
64.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
13.3
N.A.
13.3
13.3
N.A.
26.6
6.6
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
20
N.A.
26.6
13.3
N.A.
33.3
20
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
20
0
10
0
0
10
0
20
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
0
% C
% Asp:
0
20
0
0
0
20
10
0
0
20
0
0
0
0
0
% D
% Glu:
40
10
10
10
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
0
0
10
20
0
0
10
0
0
0
0
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
10
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
20
0
0
0
0
10
10
0
0
0
0
30
% K
% Leu:
0
10
10
0
10
10
0
10
30
0
0
10
40
40
0
% L
% Met:
0
0
0
0
0
0
0
30
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
20
10
0
0
0
0
0
0
% N
% Pro:
10
20
0
30
0
60
50
0
0
40
20
60
10
20
10
% P
% Gln:
0
10
10
0
0
10
0
0
10
20
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
30
% R
% Ser:
10
0
10
0
0
0
0
0
10
0
30
20
10
0
10
% S
% Thr:
0
0
0
0
10
0
0
20
0
0
0
0
20
0
10
% T
% Val:
0
10
40
0
10
0
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
10
30
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
30
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _